Validation of the Fatigue Severity Scale in Danish patients with systemic lupus erythematosus

Kristian Lorentzen, Mads Ammitzbøll Danielsen, Susan Due Kay, Anne Voss

Research output: Contribution to journalJournal articleResearchpeer-review


IntroductIon: Fatigue is a symptom of systemic lupus ery thematosus (SLE), which has a substantial effect on the patients' quality of life and is a parameter that is difficult to quantify. The Fatigue Severity Scale (FSS) is a validated and reliable tool for quantifying fatigue. However, no Danish translation has yet been developed or validated. The aim of this study was to translate the FSS from English into Danish and subsequently to test and describe its validity and reliability in Danish SLE patients. MaterIal and Methods: The FSS was translated from English into Danish and then back-translated. The translation agreed upon by medical professionals was tested for construct validity in an unselected group of SLE patients. The final version was tested for content validity, internal consistency and test-retest reliability in a second unselected group of SLE patients using the Danish version of the Short-Form Health Survey (SF-36). All patients included were outpatients with SLE of low to moderate disease activity, and low to moderate organ damage. results: Correlations were found between the Danish FSS and the main component scores of the SF-36. We found a high Cronbach's alpha as well as acceptable results of the intraclass correlation coefficient and the Bland-Altman plot. conclusIon: The Danish FSS translation is a valid and reliable measure of fatigue in the Danish SLE patients included in this study.

Original languageEnglish
JournalDanish Medical Journal
Issue number4
Pages (from-to)A4808
Number of pages4
Publication statusPublished - Apr 2014


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