Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Karam Matlub Sørensen; Charlotte Harken Jensen; Søren Paludan Sheikh; Niels Qvist; Jens Ahm Sørensen

doi:10.1093/ibd/izab276

Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Karam Matlub Sørensen^*, Charlotte Harken Jensen, Søren Paludan Sheikh, Niels Qvist, Jens Ahm Sørensen

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

Original language	English
Journal	Inflammatory Bowel Diseases
Volume	28
Issue number	6
Pages (from-to)	967-970
ISSN	1078-0998
DOIs	https://doi.org/10.1093/ibd/izab276
Publication status	Published - 3. Jun 2022

Keywords

Crohn’s disease
cell therapy
rectal fistula
stem cells
Humans
Crohn Disease/complications
Transplantation, Autologous
Treatment Outcome
Rectal Fistula/etiology
Mesenchymal Stem Cell Transplantation

Documents & Links

10.1093/ibd/izab276

1 Ph.D. thesis

Minimal invasive approach in the management of perianal suppuration disease
Sørensen, K. M., 1. Nov 2021, Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet. 78 p.
Research output: Thesis › Ph.D. thesis

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title = "Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells",

abstract = "In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.",

keywords = "Crohn{\textquoteright}s disease, cell therapy, rectal fistula, stem cells, Humans, Crohn Disease/complications, Transplantation, Autologous, Treatment Outcome, Rectal Fistula/etiology, Mesenchymal Stem Cell Transplantation",

author = "S{\o}rensen, {Karam Matlub} and Jensen, {Charlotte Harken} and Sheikh, {S{\o}ren Paludan} and Niels Qvist and S{\o}rensen, {Jens Ahm}",

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AU - Jensen, Charlotte Harken

AU - Sheikh, Søren Paludan

AU - Qvist, Niels

AU - Sørensen, Jens Ahm

PY - 2022/6/3

Y1 - 2022/6/3

N2 - In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

AB - In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

KW - Crohn’s disease

KW - cell therapy

KW - rectal fistula

KW - stem cells

KW - Humans

KW - Crohn Disease/complications

KW - Transplantation, Autologous

KW - Treatment Outcome

KW - Rectal Fistula/etiology

KW - Mesenchymal Stem Cell Transplantation

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DO - 10.1093/ibd/izab276

M3 - Journal article

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SN - 1078-0998

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JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

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ER -

Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Abstract

Keywords

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Related research output

Minimal invasive approach in the management of perianal suppuration disease

Cite this