The incidence of ulcerative colitis (1995-2011) and Crohn's disease (1995-2012) - Based on nationwide Danish registry data

Bente Mertz Nørgård, Jan Nielsen, Kirsten Fonager, Jens Kjeldsen, Bent Ascanius Jacobsen, Niels Qvist

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

BACKGROUND AND AIMS: The incidence of ulcerative colitis (UC) and Crohn's disease (CD) has increased during the 20th century in North America and Western Europe. However, there are conflicting reports whether the incidence has declined, stabilized or even continued to increase. No nationwide Danish data on the incidence of UC and CD exist after 1992, and therefore we studied the incidence of UC (1995 through 2011) and CD (1995 through 2012).

METHODS: Based on data from the Danish National Patient Registry we identified patients recorded with a first time diagnosis of UC or CD in the study periods. Among these - patients were only included in the study as incident cases if they had at least one more discharge diagnosis of UC/CD or at least three subsequent outpatient visits.

RESULTS: We identified 17,500 patients with UC and 7863 patients with CD. The mean incidence rate for UC in 1995-1998 was 14.4 per 100,000 per year for women and 13.8 for men, increasing to 23.2 per 100,000 per year for women and 23.4 for men in the period of 2009-2011. The mean incidence rate for CD in 1995-1998 was 7.8 per 100,000 per year for women and 5.6 for men, increasing to 10.3 per 100,000 per year for women and 8.9 for men in the period of 2009-2012.

CONCLUSIONS: Based on nationwide Danish data from the last two decades, the incidence rates of UC and CD have continued to increase.

Original languageEnglish
JournalJournal of Crohn's and Colitis
Volume8
Issue number10
Pages (from-to)1274-80
ISSN1873-9946
DOIs
Publication statusPublished - 1. Oct 2014

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Ulcerative Colitis
Crohn Disease
Registries
Incidence
North America
Outpatients

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@article{5a74f561734f4fbea9b040b41ce298a7,
title = "The incidence of ulcerative colitis (1995-2011) and Crohn's disease (1995-2012) - Based on nationwide Danish registry data",
abstract = "BACKGROUND AND AIMS: The incidence of ulcerative colitis (UC) and Crohn's disease (CD) has increased during the 20th century in North America and Western Europe. However, there are conflicting reports whether the incidence has declined, stabilized or even continued to increase. No nationwide Danish data on the incidence of UC and CD exist after 1992, and therefore we studied the incidence of UC (1995 through 2011) and CD (1995 through 2012).METHODS: Based on data from the Danish National Patient Registry we identified patients recorded with a first time diagnosis of UC or CD in the study periods. Among these - patients were only included in the study as incident cases if they had at least one more discharge diagnosis of UC/CD or at least three subsequent outpatient visits.RESULTS: We identified 17,500 patients with UC and 7863 patients with CD. The mean incidence rate for UC in 1995-1998 was 14.4 per 100,000 per year for women and 13.8 for men, increasing to 23.2 per 100,000 per year for women and 23.4 for men in the period of 2009-2011. The mean incidence rate for CD in 1995-1998 was 7.8 per 100,000 per year for women and 5.6 for men, increasing to 10.3 per 100,000 per year for women and 8.9 for men in the period of 2009-2012.CONCLUSIONS: Based on nationwide Danish data from the last two decades, the incidence rates of UC and CD have continued to increase.",
author = "N{\o}rg{\aa}rd, {Bente Mertz} and Jan Nielsen and Kirsten Fonager and Jens Kjeldsen and Jacobsen, {Bent Ascanius} and Niels Qvist",
note = "Copyright {\circledC} 2014 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.",
year = "2014",
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pages = "1274--80",
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The incidence of ulcerative colitis (1995-2011) and Crohn's disease (1995-2012) - Based on nationwide Danish registry data. / Nørgård, Bente Mertz; Nielsen, Jan; Fonager, Kirsten; Kjeldsen, Jens; Jacobsen, Bent Ascanius; Qvist, Niels.

In: Journal of Crohn's and Colitis, Vol. 8, No. 10, 01.10.2014, p. 1274-80.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - The incidence of ulcerative colitis (1995-2011) and Crohn's disease (1995-2012) - Based on nationwide Danish registry data

AU - Nørgård, Bente Mertz

AU - Nielsen, Jan

AU - Fonager, Kirsten

AU - Kjeldsen, Jens

AU - Jacobsen, Bent Ascanius

AU - Qvist, Niels

N1 - Copyright © 2014 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.

PY - 2014/10/1

Y1 - 2014/10/1

N2 - BACKGROUND AND AIMS: The incidence of ulcerative colitis (UC) and Crohn's disease (CD) has increased during the 20th century in North America and Western Europe. However, there are conflicting reports whether the incidence has declined, stabilized or even continued to increase. No nationwide Danish data on the incidence of UC and CD exist after 1992, and therefore we studied the incidence of UC (1995 through 2011) and CD (1995 through 2012).METHODS: Based on data from the Danish National Patient Registry we identified patients recorded with a first time diagnosis of UC or CD in the study periods. Among these - patients were only included in the study as incident cases if they had at least one more discharge diagnosis of UC/CD or at least three subsequent outpatient visits.RESULTS: We identified 17,500 patients with UC and 7863 patients with CD. The mean incidence rate for UC in 1995-1998 was 14.4 per 100,000 per year for women and 13.8 for men, increasing to 23.2 per 100,000 per year for women and 23.4 for men in the period of 2009-2011. The mean incidence rate for CD in 1995-1998 was 7.8 per 100,000 per year for women and 5.6 for men, increasing to 10.3 per 100,000 per year for women and 8.9 for men in the period of 2009-2012.CONCLUSIONS: Based on nationwide Danish data from the last two decades, the incidence rates of UC and CD have continued to increase.

AB - BACKGROUND AND AIMS: The incidence of ulcerative colitis (UC) and Crohn's disease (CD) has increased during the 20th century in North America and Western Europe. However, there are conflicting reports whether the incidence has declined, stabilized or even continued to increase. No nationwide Danish data on the incidence of UC and CD exist after 1992, and therefore we studied the incidence of UC (1995 through 2011) and CD (1995 through 2012).METHODS: Based on data from the Danish National Patient Registry we identified patients recorded with a first time diagnosis of UC or CD in the study periods. Among these - patients were only included in the study as incident cases if they had at least one more discharge diagnosis of UC/CD or at least three subsequent outpatient visits.RESULTS: We identified 17,500 patients with UC and 7863 patients with CD. The mean incidence rate for UC in 1995-1998 was 14.4 per 100,000 per year for women and 13.8 for men, increasing to 23.2 per 100,000 per year for women and 23.4 for men in the period of 2009-2011. The mean incidence rate for CD in 1995-1998 was 7.8 per 100,000 per year for women and 5.6 for men, increasing to 10.3 per 100,000 per year for women and 8.9 for men in the period of 2009-2012.CONCLUSIONS: Based on nationwide Danish data from the last two decades, the incidence rates of UC and CD have continued to increase.

U2 - 10.1016/j.crohns.2014.03.006

DO - 10.1016/j.crohns.2014.03.006

M3 - Journal article

C2 - 24675473

VL - 8

SP - 1274

EP - 1280

JO - Journal of Crohn's and Colitis

JF - Journal of Crohn's and Colitis

SN - 1873-9946

IS - 10

ER -