The incidence and clinical symptomatology of Clostridium difficile infections in a community setting in a cohort of Danish patients attending general practice

Lillian Marie Søes, H M Holt, B Böttiger, H V Nielsen, M Torpdahl, E M Nielsen, S Ethelberg, K Mølbak, V Andreasen, M Kemp, K E P Olsen

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Abstract

Clostridium difficile infection (CDI) is gradually being recognised as a cause of morbidity in the community. We investigated the incidence and clinical characteristics of CDI in a community setting and characterised the C. difficile strains by toxin gene profiling and polymerase chain reaction (PCR) ribotyping. Patients included in the study had attended general practice, primarily because of diarrhoea; CDI patients (259 patients; 121 38 °C, weight loss and sick leave. Data were analysed by logistic regression. CDI patients 15 days (59 % vs. 73 %) as the predominant symptoms. CDI patients ≥2 years old reported duration of diarrhoea >15 days more often compared to non-CDI patients (73 % vs. 27 %, p 
Original languageEnglish
JournalEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Volume33
Issue number6
Pages (from-to)957-967
ISSN0934-9723
DOIs
Publication statusPublished - 2014

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