The extension of a DNA double helix by an additional Watson-Crick base pair on the same backbone

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Abstract

Additional base pair: The DNA duplex can be extended with an additional Watson-Crick base pair on the same backbone by the use of double-headed nucleotides. These also work as compressed dinucleotides and form two base pairs with cognate nucleobases on the opposite strand.
Original languageEnglish
JournalChemBioChem
Volume14
Issue number9
Pages (from-to)1072-1074
ISSN1439-4227
DOIs
Publication statusPublished - 2013

Keywords

  • Base Pairing DNA/*chemistry/metabolism Molecular Dynamics Simulation Nucleic Acid Conformation Nucleotides/chemistry Thermodynamics

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