Abstract

The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins from birth cohorts until 2009. The DTR currently comprises of more than 175,000 twins from the 140 birth cohorts. This makes the DTR the oldest nationwide twin register and among the largest in the world. The combination of data from several surveys, including biological samples and repeated measurements on the same individuals, and data from Danish national registers provides a unique resource for a wide range of twin studies. This article provides an updated overview of the data in the DTR: First, we provide a summary of the establishment of the register, the different ascertainment methods and the twins included; then follows an overview of major surveys conducted in the DTR since 1994 and a description of the DTR biobank, including a description of the molecular data created so far; finally, a short description is given of the linkage to Danish national registers at Statistics Denmark and some recent examples of studies using the various data resources in the DTR are highlighted.

Original languageEnglish
JournalTwin Research and Human Genetics
ISSN1832-4274
DOIs
Publication statusE-pub ahead of print - 23. Sep 2019

Fingerprint

Registries
Twin Studies
Denmark

Keywords

  • biobank
  • Denmark
  • molecular
  • register-based research
  • surveys
  • Twin register

Cite this

@article{67bc359dce23462886bf186b28a31ff9,
title = "The Danish Twin Registry: An Updated Overview",
abstract = "The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins from birth cohorts until 2009. The DTR currently comprises of more than 175,000 twins from the 140 birth cohorts. This makes the DTR the oldest nationwide twin register and among the largest in the world. The combination of data from several surveys, including biological samples and repeated measurements on the same individuals, and data from Danish national registers provides a unique resource for a wide range of twin studies. This article provides an updated overview of the data in the DTR: First, we provide a summary of the establishment of the register, the different ascertainment methods and the twins included; then follows an overview of major surveys conducted in the DTR since 1994 and a description of the DTR biobank, including a description of the molecular data created so far; finally, a short description is given of the linkage to Danish national registers at Statistics Denmark and some recent examples of studies using the various data resources in the DTR are highlighted.",
keywords = "biobank, Denmark, molecular, register-based research, surveys, Twin register",
author = "Pedersen, {Dorthe Almind} and Larsen, {Lisbeth Aagaard} and Marianne Nygaard and Jonas Mengel-From and Matt Mcgue and Christine Dalg{\aa}rd and Lars Hvidberg and Jacob Hjelmborg and Axel Skytthe and Holm, {Niels V.} and Kyvik, {Kirsten Ohm} and Kaare Christensen",
year = "2019",
month = "9",
day = "23",
doi = "10.1017/thg.2019.72",
language = "English",
journal = "Twin Research and Human Genetics",
issn = "1832-4274",
publisher = "Heinemann",

}

TY - JOUR

T1 - The Danish Twin Registry

T2 - An Updated Overview

AU - Pedersen, Dorthe Almind

AU - Larsen, Lisbeth Aagaard

AU - Nygaard, Marianne

AU - Mengel-From, Jonas

AU - Mcgue, Matt

AU - Dalgård, Christine

AU - Hvidberg, Lars

AU - Hjelmborg, Jacob

AU - Skytthe, Axel

AU - Holm, Niels V.

AU - Kyvik, Kirsten Ohm

AU - Christensen, Kaare

PY - 2019/9/23

Y1 - 2019/9/23

N2 - The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins from birth cohorts until 2009. The DTR currently comprises of more than 175,000 twins from the 140 birth cohorts. This makes the DTR the oldest nationwide twin register and among the largest in the world. The combination of data from several surveys, including biological samples and repeated measurements on the same individuals, and data from Danish national registers provides a unique resource for a wide range of twin studies. This article provides an updated overview of the data in the DTR: First, we provide a summary of the establishment of the register, the different ascertainment methods and the twins included; then follows an overview of major surveys conducted in the DTR since 1994 and a description of the DTR biobank, including a description of the molecular data created so far; finally, a short description is given of the linkage to Danish national registers at Statistics Denmark and some recent examples of studies using the various data resources in the DTR are highlighted.

AB - The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins from birth cohorts until 2009. The DTR currently comprises of more than 175,000 twins from the 140 birth cohorts. This makes the DTR the oldest nationwide twin register and among the largest in the world. The combination of data from several surveys, including biological samples and repeated measurements on the same individuals, and data from Danish national registers provides a unique resource for a wide range of twin studies. This article provides an updated overview of the data in the DTR: First, we provide a summary of the establishment of the register, the different ascertainment methods and the twins included; then follows an overview of major surveys conducted in the DTR since 1994 and a description of the DTR biobank, including a description of the molecular data created so far; finally, a short description is given of the linkage to Danish national registers at Statistics Denmark and some recent examples of studies using the various data resources in the DTR are highlighted.

KW - biobank

KW - Denmark

KW - molecular

KW - register-based research

KW - surveys

KW - Twin register

U2 - 10.1017/thg.2019.72

DO - 10.1017/thg.2019.72

M3 - Journal article

JO - Twin Research and Human Genetics

JF - Twin Research and Human Genetics

SN - 1832-4274

ER -