The Danish 1905 cohort: a genetic-epidemiological nationwide survey

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

OBJECTIVES. The authors studied nonagenarians, a rapidly growing age group whose cognitive and physical abilities have yet to be investigated systematically. METHODS. All Danes born in 1905 were invited to participate in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness. RESULTS. There were 2,262 participants. A total of 1,632 (72%) gave a DNA sample. Participants and nonparticipants were highly comparable with regard to marital status, institutionalization, and hospitalization patterns, but men and rural area residents were more likely to participate. Six months after the survey began, 7.2% of the participants and 11.8% of the nonparticipants had died. DISCUSSION. Despite the known difficulties of conducting surveys among the extremely old, it was possible to conduct a nationwide survey, including collection of DNA, among more than 2,000 fairly nonselected nonagenarians using lay interviewers.
Original languageEnglish
JournalJournal of Aging and Health
Volume13
Issue number1
Pages (from-to)32-46
Number of pages14
ISSN0898-2643
DOIs
Publication statusPublished - 2001

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Interviews
DNA
Marital Status
Registries
Age Groups
Surveys and Questionnaires

Keywords

  • Aged
  • Aged, 80 and over
  • Aging
  • Cohort Studies
  • Denmark
  • Female
  • Geriatric Assessment
  • Health Surveys
  • Humans
  • Interviews as Topic
  • Male
  • Sequence Analysis, DNA

Cite this

@article{ae1bf740d01211dd9908000ea68e967b,
title = "The Danish 1905 cohort: a genetic-epidemiological nationwide survey",
abstract = "OBJECTIVES. The authors studied nonagenarians, a rapidly growing age group whose cognitive and physical abilities have yet to be investigated systematically. METHODS. All Danes born in 1905 were invited to participate in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness. RESULTS. There were 2,262 participants. A total of 1,632 (72{\%}) gave a DNA sample. Participants and nonparticipants were highly comparable with regard to marital status, institutionalization, and hospitalization patterns, but men and rural area residents were more likely to participate. Six months after the survey began, 7.2{\%} of the participants and 11.8{\%} of the nonparticipants had died. DISCUSSION. Despite the known difficulties of conducting surveys among the extremely old, it was possible to conduct a nationwide survey, including collection of DNA, among more than 2,000 fairly nonselected nonagenarians using lay interviewers.",
keywords = "Aged, Aged, 80 and over, Aging, Cohort Studies, Denmark, Female, Geriatric Assessment, Health Surveys, Humans, Interviews as Topic, Male, Sequence Analysis, DNA",
author = "H Nybo and D Gaist and B Jeune and L Bathum and M McGue and Vaupel, {J W} and Kaare Christensen",
year = "2001",
doi = "10.1177/089826430101300102",
language = "English",
volume = "13",
pages = "32--46",
journal = "Journal of Aging and Health",
issn = "0898-2643",
publisher = "SAGE Publications",
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}

The Danish 1905 cohort: a genetic-epidemiological nationwide survey. / Nybo, H; Gaist, D; Jeune, B; Bathum, L; McGue, M; Vaupel, J W; Christensen, Kaare.

In: Journal of Aging and Health, Vol. 13, No. 1, 2001, p. 32-46.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - The Danish 1905 cohort: a genetic-epidemiological nationwide survey

AU - Nybo, H

AU - Gaist, D

AU - Jeune, B

AU - Bathum, L

AU - McGue, M

AU - Vaupel, J W

AU - Christensen, Kaare

PY - 2001

Y1 - 2001

N2 - OBJECTIVES. The authors studied nonagenarians, a rapidly growing age group whose cognitive and physical abilities have yet to be investigated systematically. METHODS. All Danes born in 1905 were invited to participate in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness. RESULTS. There were 2,262 participants. A total of 1,632 (72%) gave a DNA sample. Participants and nonparticipants were highly comparable with regard to marital status, institutionalization, and hospitalization patterns, but men and rural area residents were more likely to participate. Six months after the survey began, 7.2% of the participants and 11.8% of the nonparticipants had died. DISCUSSION. Despite the known difficulties of conducting surveys among the extremely old, it was possible to conduct a nationwide survey, including collection of DNA, among more than 2,000 fairly nonselected nonagenarians using lay interviewers.

AB - OBJECTIVES. The authors studied nonagenarians, a rapidly growing age group whose cognitive and physical abilities have yet to be investigated systematically. METHODS. All Danes born in 1905 were invited to participate in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness. RESULTS. There were 2,262 participants. A total of 1,632 (72%) gave a DNA sample. Participants and nonparticipants were highly comparable with regard to marital status, institutionalization, and hospitalization patterns, but men and rural area residents were more likely to participate. Six months after the survey began, 7.2% of the participants and 11.8% of the nonparticipants had died. DISCUSSION. Despite the known difficulties of conducting surveys among the extremely old, it was possible to conduct a nationwide survey, including collection of DNA, among more than 2,000 fairly nonselected nonagenarians using lay interviewers.

KW - Aged

KW - Aged, 80 and over

KW - Aging

KW - Cohort Studies

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KW - Geriatric Assessment

KW - Health Surveys

KW - Humans

KW - Interviews as Topic

KW - Male

KW - Sequence Analysis, DNA

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