Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000–2016: a Danish population-based study

Lasse Hjort Jakobsen*, Anne Stidsholt Roug, Andreas Kiesbye Øvlisen, Claus Werenberg Marcher, Hans Beier Ommen, Kim Theilgaard-Mönch, Peter Møller, Claudia Schöllkopf, Daniel Kristensen, Therese Maria Henriette Naur, Martin Bøgsted, Tarec Christoffer El-Galaly, Marianne Tang Severinsen

*Corresponding author for this work

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Abstract

In the present study, we quantify the progress in overall survival (OS) during the period 2000–2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50–75 years and a small absolute increase in those aged >75 years.

Original languageEnglish
JournalBritish Journal of Haematology
Volume193
Issue number3
Pages (from-to)482-487
ISSN0007-1048
DOIs
Publication statusPublished - May 2021

Keywords

  • acute myeloid leukaemia
  • real-world patients
  • temporal survival

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