Sustained long-term efficacy of motivational counselling and text message reminders on daily sitting time in patients with rheumatoid arthritis?

Long-term follow-up of a randomized, parallel-group trial

Tanja Thomsen, Mette Aadahl, Nina Beyer, Merete L Hetland, Katrine B Løppenthin, Julie Midtgaard, Robin Christensen, Sabrina M Nielsen, Mikkel Østergaard, Poul Jennum, Bente A Esbensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

OBJECTIVE: To evaluate the 18-month post-intervention efficacy following a four-month individually tailored, behavioral intervention on daily sitting time in patients with rheumatoid arthritis (RA). The four-month post-intervention results showed that patients in the intervention reduced their daily sitting time, improved patient-reported outcomes and total cholesterol levels compared to the control group.

METHODS: In an observer-blinded randomized trial, 150 RA patients were included. During four months, the intervention group (n=75) received three motivational counselling sessions and tailored text messages aimed at increasing light-intensity physical activity through reduction of sedentary behavior. The control group (n=75) maintained usual lifestyle. Primary outcome was change from baseline to 18 months post intervention in objectively measured daily sitting time (ActivPAL). Secondary outcomes included changes in clinical patient-reported outcomes and cardio-metabolic biomarkers. A mixed effect repeated measures ANCOVA model in the intention-to-treat population was applied.

RESULTS: At 22-months follow-up from baseline, 12 participants were lost to follow-up. Compared to baseline, sitting time in the intervention group decreased 1.10 h/day, whereas it increased by 1.32 h/day in the control group; between-group difference of -2.43 h/day (95%CI: -2.99;-1.86; p<0.0001) favoring the intervention group. For most secondary outcomes between-group differences favored the intervention: VAS-pain: -15.51 mm (-23.42;-7.60), VAS-fatigue: -12.30 mm (-20.71;-3.88), physical function: -0.39 HAQ-units (-0.53;-0.26), total cholesterol: -0.86 (-1.03;-0.68), triglyceride: -0.26 (-0.43;-0.09) and average glucose: -1.15 (-1.39;-0.91) mmol/l.

CONCLUSION: Eighteen months after intervention, patients in the intervention group were still significantly less sedentary than controls. Findings suggest that a behavioral approach is beneficial for promoting long-term physical activity and health in patients with RA.

Original languageEnglish
JournalArthritis Care & Research
ISSN2151-464X
DOIs
Publication statusE-pub ahead of print - 10. Sep 2019

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Text Messaging
Counseling
Control Groups
Exercise
Health
Population

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Thomsen, Tanja ; Aadahl, Mette ; Beyer, Nina ; Hetland, Merete L ; Løppenthin, Katrine B ; Midtgaard, Julie ; Christensen, Robin ; Nielsen, Sabrina M ; Østergaard, Mikkel ; Jennum, Poul ; Esbensen, Bente A. / Sustained long-term efficacy of motivational counselling and text message reminders on daily sitting time in patients with rheumatoid arthritis? Long-term follow-up of a randomized, parallel-group trial. In: Arthritis Care & Research. 2019.
@article{ab816047e1bf4114b52cc761cf2e0a7e,
title = "Sustained long-term efficacy of motivational counselling and text message reminders on daily sitting time in patients with rheumatoid arthritis?: Long-term follow-up of a randomized, parallel-group trial",
abstract = "OBJECTIVE: To evaluate the 18-month post-intervention efficacy following a four-month individually tailored, behavioral intervention on daily sitting time in patients with rheumatoid arthritis (RA). The four-month post-intervention results showed that patients in the intervention reduced their daily sitting time, improved patient-reported outcomes and total cholesterol levels compared to the control group.METHODS: In an observer-blinded randomized trial, 150 RA patients were included. During four months, the intervention group (n=75) received three motivational counselling sessions and tailored text messages aimed at increasing light-intensity physical activity through reduction of sedentary behavior. The control group (n=75) maintained usual lifestyle. Primary outcome was change from baseline to 18 months post intervention in objectively measured daily sitting time (ActivPAL). Secondary outcomes included changes in clinical patient-reported outcomes and cardio-metabolic biomarkers. A mixed effect repeated measures ANCOVA model in the intention-to-treat population was applied.RESULTS: At 22-months follow-up from baseline, 12 participants were lost to follow-up. Compared to baseline, sitting time in the intervention group decreased 1.10 h/day, whereas it increased by 1.32 h/day in the control group; between-group difference of -2.43 h/day (95{\%}CI: -2.99;-1.86; p<0.0001) favoring the intervention group. For most secondary outcomes between-group differences favored the intervention: VAS-pain: -15.51 mm (-23.42;-7.60), VAS-fatigue: -12.30 mm (-20.71;-3.88), physical function: -0.39 HAQ-units (-0.53;-0.26), total cholesterol: -0.86 (-1.03;-0.68), triglyceride: -0.26 (-0.43;-0.09) and average glucose: -1.15 (-1.39;-0.91) mmol/l.CONCLUSION: Eighteen months after intervention, patients in the intervention group were still significantly less sedentary than controls. Findings suggest that a behavioral approach is beneficial for promoting long-term physical activity and health in patients with RA.",
author = "Tanja Thomsen and Mette Aadahl and Nina Beyer and Hetland, {Merete L} and L{\o}ppenthin, {Katrine B} and Julie Midtgaard and Robin Christensen and Nielsen, {Sabrina M} and Mikkel {\O}stergaard and Poul Jennum and Esbensen, {Bente A}",
note = "{\circledC} 2019, American College of Rheumatology.",
year = "2019",
month = "9",
day = "10",
doi = "10.1002/acr.24060",
language = "English",
journal = "Arthritis Care & Research",
issn = "2151-464X",
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Sustained long-term efficacy of motivational counselling and text message reminders on daily sitting time in patients with rheumatoid arthritis? Long-term follow-up of a randomized, parallel-group trial. / Thomsen, Tanja; Aadahl, Mette; Beyer, Nina; Hetland, Merete L; Løppenthin, Katrine B; Midtgaard, Julie; Christensen, Robin; Nielsen, Sabrina M; Østergaard, Mikkel; Jennum, Poul; Esbensen, Bente A.

In: Arthritis Care & Research, 10.09.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Sustained long-term efficacy of motivational counselling and text message reminders on daily sitting time in patients with rheumatoid arthritis?

T2 - Long-term follow-up of a randomized, parallel-group trial

AU - Thomsen, Tanja

AU - Aadahl, Mette

AU - Beyer, Nina

AU - Hetland, Merete L

AU - Løppenthin, Katrine B

AU - Midtgaard, Julie

AU - Christensen, Robin

AU - Nielsen, Sabrina M

AU - Østergaard, Mikkel

AU - Jennum, Poul

AU - Esbensen, Bente A

N1 - © 2019, American College of Rheumatology.

PY - 2019/9/10

Y1 - 2019/9/10

N2 - OBJECTIVE: To evaluate the 18-month post-intervention efficacy following a four-month individually tailored, behavioral intervention on daily sitting time in patients with rheumatoid arthritis (RA). The four-month post-intervention results showed that patients in the intervention reduced their daily sitting time, improved patient-reported outcomes and total cholesterol levels compared to the control group.METHODS: In an observer-blinded randomized trial, 150 RA patients were included. During four months, the intervention group (n=75) received three motivational counselling sessions and tailored text messages aimed at increasing light-intensity physical activity through reduction of sedentary behavior. The control group (n=75) maintained usual lifestyle. Primary outcome was change from baseline to 18 months post intervention in objectively measured daily sitting time (ActivPAL). Secondary outcomes included changes in clinical patient-reported outcomes and cardio-metabolic biomarkers. A mixed effect repeated measures ANCOVA model in the intention-to-treat population was applied.RESULTS: At 22-months follow-up from baseline, 12 participants were lost to follow-up. Compared to baseline, sitting time in the intervention group decreased 1.10 h/day, whereas it increased by 1.32 h/day in the control group; between-group difference of -2.43 h/day (95%CI: -2.99;-1.86; p<0.0001) favoring the intervention group. For most secondary outcomes between-group differences favored the intervention: VAS-pain: -15.51 mm (-23.42;-7.60), VAS-fatigue: -12.30 mm (-20.71;-3.88), physical function: -0.39 HAQ-units (-0.53;-0.26), total cholesterol: -0.86 (-1.03;-0.68), triglyceride: -0.26 (-0.43;-0.09) and average glucose: -1.15 (-1.39;-0.91) mmol/l.CONCLUSION: Eighteen months after intervention, patients in the intervention group were still significantly less sedentary than controls. Findings suggest that a behavioral approach is beneficial for promoting long-term physical activity and health in patients with RA.

AB - OBJECTIVE: To evaluate the 18-month post-intervention efficacy following a four-month individually tailored, behavioral intervention on daily sitting time in patients with rheumatoid arthritis (RA). The four-month post-intervention results showed that patients in the intervention reduced their daily sitting time, improved patient-reported outcomes and total cholesterol levels compared to the control group.METHODS: In an observer-blinded randomized trial, 150 RA patients were included. During four months, the intervention group (n=75) received three motivational counselling sessions and tailored text messages aimed at increasing light-intensity physical activity through reduction of sedentary behavior. The control group (n=75) maintained usual lifestyle. Primary outcome was change from baseline to 18 months post intervention in objectively measured daily sitting time (ActivPAL). Secondary outcomes included changes in clinical patient-reported outcomes and cardio-metabolic biomarkers. A mixed effect repeated measures ANCOVA model in the intention-to-treat population was applied.RESULTS: At 22-months follow-up from baseline, 12 participants were lost to follow-up. Compared to baseline, sitting time in the intervention group decreased 1.10 h/day, whereas it increased by 1.32 h/day in the control group; between-group difference of -2.43 h/day (95%CI: -2.99;-1.86; p<0.0001) favoring the intervention group. For most secondary outcomes between-group differences favored the intervention: VAS-pain: -15.51 mm (-23.42;-7.60), VAS-fatigue: -12.30 mm (-20.71;-3.88), physical function: -0.39 HAQ-units (-0.53;-0.26), total cholesterol: -0.86 (-1.03;-0.68), triglyceride: -0.26 (-0.43;-0.09) and average glucose: -1.15 (-1.39;-0.91) mmol/l.CONCLUSION: Eighteen months after intervention, patients in the intervention group were still significantly less sedentary than controls. Findings suggest that a behavioral approach is beneficial for promoting long-term physical activity and health in patients with RA.

U2 - 10.1002/acr.24060

DO - 10.1002/acr.24060

M3 - Journal article

JO - Arthritis Care & Research

JF - Arthritis Care & Research

SN - 2151-464X

ER -