Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful female trapezius muscle

Abigail Louise Mackey, Lars L Andersen, Ulrik Frandsen, Gisela Sjøgaard

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

While strength training has been shown to be effective in mediating hypertrophy and reducing pain in trapezius myalgia, responses at the cellular level have not previously been studied. This study investigated the potential of strength training targeting the affected muscles (SST, n=18) and general fitness training (GFT, n=16) to augment the satellite cell (SC) and macrophage pools in the trapezius muscles of women diagnosed with trapezius myalgia. A group receiving general health information (REF, n=8) served as a control. Muscle biopsies were collected from the trapezius muscles of the 42 women (age 44 ± 8 yrs; mean ± SD) before and after the 10-week intervention period and were analysed by immunohistochemistry for SCs, macrophages, and myonuclei. The SC content of type I and II fibres was observed to increase significantly from baseline by 65% and 164%, respectively, with SST (P
Original languageEnglish
JournalJournal of Physiology
Volume589
Issue number22
Pages (from-to)5503–5515
ISSN0022-3751
DOIs
Publication statusPublished - Jan 2011

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Superficial Back Muscles
Resistance Training
Cell Size
Myalgia
Macrophages
Muscles
Health

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title = "Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful female trapezius muscle",
abstract = "While strength training has been shown to be effective in mediating hypertrophy and reducing pain in trapezius myalgia, responses at the cellular level have not previously been studied. This study investigated the potential of strength training targeting the affected muscles (SST, n=18) and general fitness training (GFT, n=16) to augment the satellite cell (SC) and macrophage pools in the trapezius muscles of women diagnosed with trapezius myalgia. A group receiving general health information (REF, n=8) served as a control. Muscle biopsies were collected from the trapezius muscles of the 42 women (age 44 ± 8 yrs; mean ± SD) before and after the 10-week intervention period and were analysed by immunohistochemistry for SCs, macrophages, and myonuclei. The SC content of type I and II fibres was observed to increase significantly from baseline by 65{\%} and 164{\%}, respectively, with SST (P",
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Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful female trapezius muscle. / Mackey, Abigail Louise; Andersen, Lars L; Frandsen, Ulrik; Sjøgaard, Gisela.

In: Journal of Physiology, Vol. 589, No. 22, 01.2011, p. 5503–5515.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful female trapezius muscle

AU - Mackey, Abigail Louise

AU - Andersen, Lars L

AU - Frandsen, Ulrik

AU - Sjøgaard, Gisela

PY - 2011/1

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N2 - While strength training has been shown to be effective in mediating hypertrophy and reducing pain in trapezius myalgia, responses at the cellular level have not previously been studied. This study investigated the potential of strength training targeting the affected muscles (SST, n=18) and general fitness training (GFT, n=16) to augment the satellite cell (SC) and macrophage pools in the trapezius muscles of women diagnosed with trapezius myalgia. A group receiving general health information (REF, n=8) served as a control. Muscle biopsies were collected from the trapezius muscles of the 42 women (age 44 ± 8 yrs; mean ± SD) before and after the 10-week intervention period and were analysed by immunohistochemistry for SCs, macrophages, and myonuclei. The SC content of type I and II fibres was observed to increase significantly from baseline by 65% and 164%, respectively, with SST (P

AB - While strength training has been shown to be effective in mediating hypertrophy and reducing pain in trapezius myalgia, responses at the cellular level have not previously been studied. This study investigated the potential of strength training targeting the affected muscles (SST, n=18) and general fitness training (GFT, n=16) to augment the satellite cell (SC) and macrophage pools in the trapezius muscles of women diagnosed with trapezius myalgia. A group receiving general health information (REF, n=8) served as a control. Muscle biopsies were collected from the trapezius muscles of the 42 women (age 44 ± 8 yrs; mean ± SD) before and after the 10-week intervention period and were analysed by immunohistochemistry for SCs, macrophages, and myonuclei. The SC content of type I and II fibres was observed to increase significantly from baseline by 65% and 164%, respectively, with SST (P

U2 - 10.1113/jphysiol.2011.217885

DO - 10.1113/jphysiol.2011.217885

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