Stiff person syndrome er fortsat en vanskelig og overset diagnose

Translated title of the contribution: Stiff person syndrome: still a difficult and overlooked diagnosis

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

We present a case of stiff person syndrome (SPS) with a description of the diagnostic challenges and a discussion of the implication of novel antibodies. SPS is a rare neurological disorder presenting with severe rigidity, muscle spasms and impaired gait function, and diagnosis is often delayed due to low awareness. SPS is classically associated with antibodies directed against glutamic acid decarboxylase or amphiphysin. However, recent advances have contributed to our understanding because of detection of several new antibodies, which cause SPS, mostly with additional neurological/systemic manifestations.
Original languageDanish
Article numberV03190166
JournalUgeskrift for Laeger
Volume181
ISSN0041-5782
Publication statusE-pub ahead of print - 2. Sep 2019

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Stiff-Person Syndrome
Glutamate Decarboxylase
Nervous System Diseases

Cite this

@article{783bea65f34742fb908eecc0a082f3ad,
title = "Stiff person syndrome er fortsat en vanskelig og overset diagnose",
abstract = "We present a case of stiff person syndrome (SPS) with a description of the diagnostic challenges and a discussion of the implication of novel antibodies. SPS is a rare neurological disorder presenting with severe rigidity, muscle spasms and impaired gait function, and diagnosis is often delayed due to low awareness. SPS is classically associated with antibodies directed against glutamic acid decarboxylase or amphiphysin. However, recent advances have contributed to our understanding because of detection of several new antibodies, which cause SPS, mostly with additional neurological/systemic manifestations.",
author = "Nissen, {Mette Scheller} and Jonatan Forsberg and Matthias Bode and Morten Blaabjerg",
year = "2019",
month = "9",
day = "2",
language = "Dansk",
volume = "181",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",

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Stiff person syndrome er fortsat en vanskelig og overset diagnose. / Nissen, Mette Scheller; Forsberg, Jonatan; Bode, Matthias; Blaabjerg, Morten.

In: Ugeskrift for Laeger, Vol. 181, V03190166, 02.09.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Stiff person syndrome er fortsat en vanskelig og overset diagnose

AU - Nissen, Mette Scheller

AU - Forsberg, Jonatan

AU - Bode, Matthias

AU - Blaabjerg, Morten

PY - 2019/9/2

Y1 - 2019/9/2

N2 - We present a case of stiff person syndrome (SPS) with a description of the diagnostic challenges and a discussion of the implication of novel antibodies. SPS is a rare neurological disorder presenting with severe rigidity, muscle spasms and impaired gait function, and diagnosis is often delayed due to low awareness. SPS is classically associated with antibodies directed against glutamic acid decarboxylase or amphiphysin. However, recent advances have contributed to our understanding because of detection of several new antibodies, which cause SPS, mostly with additional neurological/systemic manifestations.

AB - We present a case of stiff person syndrome (SPS) with a description of the diagnostic challenges and a discussion of the implication of novel antibodies. SPS is a rare neurological disorder presenting with severe rigidity, muscle spasms and impaired gait function, and diagnosis is often delayed due to low awareness. SPS is classically associated with antibodies directed against glutamic acid decarboxylase or amphiphysin. However, recent advances have contributed to our understanding because of detection of several new antibodies, which cause SPS, mostly with additional neurological/systemic manifestations.

M3 - Tidsskriftartikel

VL - 181

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

M1 - V03190166

ER -