Speckle-Free CGH Modality for Fully Parallel Circuit Optogenetics

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

The powerful neuroscientific discipline of optogenetics can be described as the branch of biotechnology which combines genetic engineering with optics to observe and control the function of genetically targeted groups of cells with light. Using advanced volumetric laser beam-shaping such as new Deep Learning-based Computer Generated Holography (CGH) makes it possible to take advantage of cutting-edge two-photon technology to develop an unprecedented ‘circuit optogenetics’ platform with both high spatio-temporal selectivity and high penetration depth without disturbing speckle-noise in living neural tissue. We will discuss our most recent CGH-encoding modalities designed for fully parallel circuit optogenetics.

Original languageEnglish
Title of host publicationDigital Holography and Three-Dimensional Imaging 2022
PublisherOptica Publishing Group
Publication date2022
Article numberW3A.7
ISBN (Electronic)978-1-957171-12-8
DOIs
Publication statusPublished - 2022
EventDigital Holography and Three-Dimensional Imaging, DH 2022 - Cambridge, United Kingdom
Duration: 1. Aug 20224. Aug 2022

Conference

ConferenceDigital Holography and Three-Dimensional Imaging, DH 2022
Country/TerritoryUnited Kingdom
CityCambridge
Period01/08/202204/08/2022
SeriesOptics InfoBase Conference Papers

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