Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration

Ahmed Al-Djaber; Albin Österroos; Alessandro Baldi; Arielle R. Munters; Nikolaj Juul Nitschke; Klas Raaschou-Jensen; Claudia Schöllkopf; Marianne Tang Severinsen; Tatjana Pandzic; Manja Meggendorfer; Joachim Weischenfeldt; Anne Stidsholt Roug; Kirsten Grønbæk; Claes Ladenvall; Torsten Haferlach; Claudia Haferlach; Thale Kristin Olsen; Panagiotis Baliakas

doi:10.1002/hem3.70452

Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration

Ahmed Al-Djaber
, Albin Österroos
, Alessandro Baldi
, Arielle R. Munters
, Nikolaj Juul Nitschke
, Klas Raaschou-Jensen
, Claudia Schöllkopf
, Marianne Tang Severinsen
, Tatjana Pandzic
, Manja Meggendorfer
, Joachim Weischenfeldt
, Anne Stidsholt Roug
, Kirsten Grønbæk
, Claes Ladenvall
, Torsten Haferlach
, Claudia Haferlach
, Thale Kristin Olsen
, Panagiotis Baliakas^*

^*Corresponding author for this work

KI, OUH, Research unit of Haematology (Odense)

Uppsala University
Uppsala University Hospital
Munich Leukemia Laboratory
Rigshospitalet
University of Copenhagen
Aalborg University Hospital
Aalborg University
Aarhus University Hospital

Research output: Contribution to journal › Comment/debate › Research › peer-review

Original language	English
Article number	e70452
Journal	HemaSphere
Volume	10
Issue number	8
Number of pages	5
ISSN	2572-9241
DOIs	https://doi.org/10.1002/hem3.70452
Publication status	Published - Aug 2026

Funding

A.A.‐D. received support from ALF Kansliet Uppsala (LUL‐990593). P.B. received support from ALF Kansliet Uppsala (ALF‐990591, ALF‐1002575, and ALF‐991381, Swedish Society of Medicine (SLS‐961271), Lions CancerFonden (2022‐1050146 and 2023‐1050180), Vleugels stiftelse (2020‐01), Jeansson Stiftelser (2023), and Swedish Cancer Society (23 2745 Pj, Projekt). T.K.O. received funding from the Swedish Childhood Cancer Foundation (Barncancerfonden, TJ2021‐0010).

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Cite this

Al-Djaber, A., Österroos, A., Baldi, A., Munters, A. R., Nitschke, N. J., Raaschou-Jensen, K., Schöllkopf, C., Severinsen, M. T., Pandzic, T., Meggendorfer, M., Weischenfeldt, J., Roug, A. S., Grønbæk, K., Ladenvall, C., Haferlach, T., Haferlach, C., Olsen, T. K., & Baliakas, P. (2026). Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration. HemaSphere, 10(8), Article e70452. https://doi.org/10.1002/hem3.70452

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title = "Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration",

author = "Ahmed Al-Djaber and Albin {\"O}sterroos and Alessandro Baldi and Munters, \{Arielle R.\} and Nitschke, \{Nikolaj Juul\} and Klas Raaschou-Jensen and Claudia Sch{\"o}llkopf and Severinsen, \{Marianne Tang\} and Tatjana Pandzic and Manja Meggendorfer and Joachim Weischenfeldt and Roug, \{Anne Stidsholt\} and Kirsten Gr{\o}nb{\ae}k and Claes Ladenvall and Torsten Haferlach and Claudia Haferlach and Olsen, \{Thale Kristin\} and Panagiotis Baliakas",

year = "2026",

month = aug,

doi = "10.1002/hem3.70452",

language = "English",

volume = "10",

journal = "HemaSphere",

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Al-Djaber, A, Österroos, A, Baldi, A, Munters, AR, Nitschke, NJ, Raaschou-Jensen, K, Schöllkopf, C, Severinsen, MT, Pandzic, T, Meggendorfer, M, Weischenfeldt, J, Roug, AS, Grønbæk, K, Ladenvall, C, Haferlach, T, Haferlach, C, Olsen, TK & Baliakas, P 2026, 'Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration', HemaSphere, vol. 10, no. 8, e70452. https://doi.org/10.1002/hem3.70452

TY - JOUR

T1 - Somatic RUNX1 exonic deletions in myelodysplastic syndrome

T2 - A rare yet high-risk recurrent genetic aberration

AU - Al-Djaber, Ahmed

AU - Österroos, Albin

AU - Baldi, Alessandro

AU - Munters, Arielle R.

AU - Nitschke, Nikolaj Juul

AU - Raaschou-Jensen, Klas

AU - Schöllkopf, Claudia

AU - Severinsen, Marianne Tang

AU - Pandzic, Tatjana

AU - Meggendorfer, Manja

AU - Weischenfeldt, Joachim

AU - Roug, Anne Stidsholt

AU - Grønbæk, Kirsten

AU - Ladenvall, Claes

AU - Haferlach, Torsten

AU - Haferlach, Claudia

AU - Olsen, Thale Kristin

AU - Baliakas, Panagiotis

PY - 2026/8

Y1 - 2026/8

U2 - 10.1002/hem3.70452

DO - 10.1002/hem3.70452

M3 - Comment/debate

C2 - 42630788

AN - SCOPUS:105048014132

SN - 2572-9241

VL - 10

JO - HemaSphere

JF - HemaSphere

IS - 8

M1 - e70452

ER -