Sodium retention by uPA-plasmin-ENaC in nephrotic syndrome-Authors reply

Gitte R Hinrichs, Kathrin Weyer, Ulla G Friis, Per Svenningsen, Ida Katrine Lund, Rikke Nielsen, Géraldine Mollet, Corinne Antignac, Claus Bistrup, Boye L Jensen, Henrik Birn

Research output: Contribution to journalComment/debateResearchpeer-review

Abstract

There is a great interest in exploring the mechanisms of oedema in nephrotic syndrome (NS) as evidenced by 2 parallel studies published in Acta Physiologica (1, 2). This has generated an editorial comment (3) which we respond to by this rebuttal. The interest in the nephrotic edema reflects not only the significant negative impact this has on the quality of life, but also the difficulties associated with identifying optimal treatment due to the lack of pathophysiological insight.

Original languageEnglish
Article numbere13432
JournalActa Physiologica (Print)
Volume228
Issue number4
ISSN1748-1708
DOIs
Publication statusPublished - Apr 2020

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