SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients

Patrícia Moniz, Sérgio Brito, Pedro Póvoa*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review


The SARS-CoV-2 pandemic has placed great strain on the most developed of health care systems, especially in the context of critical care. Although co-infections with cytomegalovirus (CMV) are frequent in the critically ill due to underlying immune suppression of multiple causes, the impact on COVID-19 patients remains unclear. Furthermore, severe COVID-19 has recently been associated with significant immune suppression, and this may in turn impact CMV reactivation, possibly contributing to clinical course. Nevertheless, multiple confounding factors in these patients will certainly challenge upcoming research. The authors present a case series of five patients admitted to the intensive care unit (ICU) in the context of respiratory failure due to severe COVID-19. All patients evolved with CMV reactivation during ICU stay.

Original languageEnglish
Article number2792
JournalJournal of Clinical Medicine
Issue number13
Number of pages5
Publication statusPublished - 1. Jul 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.


  • Co-infections
  • COVID-19
  • Critical care
  • Cytomegalovirus
  • SARS-CoV-2


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