Salivary cortisol and sleep problems among civil servants

Åse Marie Hansen, Jane Frølund Thomsen, Anette Kaergaard, Henrik Albert Kolstad, Linda Kaerlev, Ole Mors, Reiner Ernst Rugulies, Jens Peter Bonde, Johan Hvid Andersen, Sigurd Mikkelsen

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OBJECTIVE: The present study used information from a field study conducted among 4489 civil servants (70% women) in Denmark in 2007. The purpose was to examine the association between sleep problems and salivary cortisol by using a cross-sectional design with repeated measures in a subsample three-month later. METHODS: Sleep problems during the past night and the past 4 weeks were assessed by a self-administered questionnaire on overall sleep quality, disturbed sleep, sleep length and awakening problems. Saliva samples were collected in a single day, using cotton tubes, 30min after awakening and again at 2000h. A subsample of 387 participants collected saliva samples three-month later at awakening, +20min and +40min after awakening and at 2000h. We adjusted for confounders related to sampling time, life style and personal characteristics, socioeconomic status and work aspects. RESULTS: Sleep problems during the past four weeks were associated with low morning and evening saliva cortisol concentrations: [-3.1% per score of disturbed sleep (p=.009); and -4.7% per score of awakening problems (p
Original languageEnglish
Issue number7
Pages (from-to)1086-1095
Publication statusPublished - 2012

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    Hansen, Å. M., Thomsen, J. F., Kaergaard, A., Kolstad, H. A., Kaerlev, L., Mors, O., Rugulies, R. E., Bonde, J. P., Andersen, J. H., & Mikkelsen, S. (2012). Salivary cortisol and sleep problems among civil servants. Psychoneuroendocrinology, 37(7), 1086-1095.