Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training

Michael Nyberg, Lasse G Jensen, Pia Thaning, Ylva Hellsten, Stefan Mortensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

We examined the role of nitric oxide (NO) and prostanoids in the regulation of leg blood flow and systemic blood pressure before and after 8 weeks of aerobic high-intensity training in individuals with essential hypertension (n = 10) and matched healthy control subjects (n = 11). Hypertensive subjects were found to have a lower (P
Original languageEnglish
JournalJournal of Physiology
Volume590
Issue numberPt 6
Pages (from-to)1481-94
Number of pages14
ISSN0022-3751
DOIs
Publication statusPublished - 15. Mar 2012
Externally publishedYes

Fingerprint

Leg
Nitric Oxide
Essential Hypertension

Keywords

  • Acetylcholine
  • Blood Pressure
  • Cyclooxygenase Inhibitors
  • Enzyme Inhibitors
  • Exercise
  • Female
  • Humans
  • Hypertension
  • Indomethacin
  • Leg
  • Male
  • Middle Aged
  • Muscle, Skeletal
  • Nitric Oxide
  • Nitric Oxide Synthase Type I
  • Nitric Oxide Synthase Type III
  • Prostaglandins
  • Regional Blood Flow
  • Vasodilation
  • omega-N-Methylarginine

Cite this

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title = "Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training",
abstract = "We examined the role of nitric oxide (NO) and prostanoids in the regulation of leg blood flow and systemic blood pressure before and after 8 weeks of aerobic high-intensity training in individuals with essential hypertension (n = 10) and matched healthy control subjects (n = 11). Hypertensive subjects were found to have a lower (P",
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language = "English",
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Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension : effect of high-intensity aerobic training. / Nyberg, Michael; Jensen, Lasse G; Thaning, Pia; Hellsten, Ylva; Mortensen, Stefan.

In: Journal of Physiology, Vol. 590, No. Pt 6, 15.03.2012, p. 1481-94.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension

T2 - effect of high-intensity aerobic training

AU - Nyberg, Michael

AU - Jensen, Lasse G

AU - Thaning, Pia

AU - Hellsten, Ylva

AU - Mortensen, Stefan

PY - 2012/3/15

Y1 - 2012/3/15

N2 - We examined the role of nitric oxide (NO) and prostanoids in the regulation of leg blood flow and systemic blood pressure before and after 8 weeks of aerobic high-intensity training in individuals with essential hypertension (n = 10) and matched healthy control subjects (n = 11). Hypertensive subjects were found to have a lower (P

AB - We examined the role of nitric oxide (NO) and prostanoids in the regulation of leg blood flow and systemic blood pressure before and after 8 weeks of aerobic high-intensity training in individuals with essential hypertension (n = 10) and matched healthy control subjects (n = 11). Hypertensive subjects were found to have a lower (P

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KW - Blood Pressure

KW - Cyclooxygenase Inhibitors

KW - Enzyme Inhibitors

KW - Exercise

KW - Female

KW - Humans

KW - Hypertension

KW - Indomethacin

KW - Leg

KW - Male

KW - Middle Aged

KW - Muscle, Skeletal

KW - Nitric Oxide

KW - Nitric Oxide Synthase Type I

KW - Nitric Oxide Synthase Type III

KW - Prostaglandins

KW - Regional Blood Flow

KW - Vasodilation

KW - omega-N-Methylarginine

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DO - 10.1113/jphysiol.2011.225136

M3 - Journal article

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VL - 590

SP - 1481

EP - 1494

JO - Journal of Physiology

JF - Journal of Physiology

SN - 0022-3751

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