Reversing Type 2 Diabetes in a Primary Care-Anchored eHealth Lifestyle Coaching Programme in Denmark: A Randomised Controlled Trial

Jeanette Reffstrup Christensen; Ditte Hjorth Laursen; Jørgen Tranekjær Lauridsen; Laura Hesseldal; Pernille Ravn Jakobsen; Jesper Bo Nielsen; Jens Søndergaard; Carl Joakim Brandt

doi:10.3390/nu14163424

Reversing Type 2 Diabetes in a Primary Care-Anchored eHealth Lifestyle Coaching Programme in Denmark: A Randomised Controlled Trial

Jeanette Reffstrup Christensen^*, Ditte Hjorth Laursen, Jørgen Tranekjær Lauridsen, Laura Hesseldal, Pernille Ravn Jakobsen, Jesper Bo Nielsen, Jens Søndergaard, Carl Joakim Brandt

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

The goal of this trial was to investigate whether an eHealth lifestyle coaching programme led to significant weight loss and decreased Haemoglobin A1c (HbA1c) in patients with type 2 diabetes. In an RCT, 170 patients were enrolled from 2018 to 2019 for intervention or control. Inclusion criteria were diagnosed with type 2 diabetes, BMI 30–45 kg/m ², and aged 18–70 years. Exclusion criteria were lacks internet access, pregnant or planning a pregnancy, or has a serious disease. Primary and secondary outcomes were a reduction in body weight and HbA1c. At six months, 75 (75%) patients in the intervention group and 53 (76%) patients in the control group remained in the trial. The mean body weight loss was 4.2 kg (95% CI, −5.49; −2.98) in the intervention group and 1.5 kg (95% CI, −2.57; −0.48) in the control group (p = 0.005). In the intervention group, 24 out of 62 patients with elevated HbA1c at baseline (39%) had a normalized HbA1c < 6.5% at six months, compared to 8 out of 40 patients with elevated HbA1c at baseline (20%) in the control group (p = 0.047). The eHealth lifestyle coaching programme can lead to significant weight loss and decreased HbA1c among patients with type 2 diabetes, compared to standard care.

Original language	English
Article number	3424
Journal	Nutrients
Volume	14
Issue number	16
ISSN	2072-6643
DOIs	https://doi.org/10.3390/nu14163424
Publication status	Published - 19. Aug 2022

Keywords

Denmark
Diabetes Mellitus, Type 2/therapy
Glycated Hemoglobin A/analysis
Humans
Life Style
Mentoring
Primary Health Care
Telemedicine
Weight Loss
telemedicine
health behaviour change
digital behavioural coaching
lifestyle change
mobile intervention
participant engagement
interactive advice
quality of life
obesity

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10.3390/nu14163424Licence: CC BY

nutrients-14-03424-v2Final published version, 412 KBLicence: CC BY

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title = "Reversing Type 2 Diabetes in a Primary Care-Anchored eHealth Lifestyle Coaching Programme in Denmark: A Randomised Controlled Trial",

abstract = "The goal of this trial was to investigate whether an eHealth lifestyle coaching programme led to significant weight loss and decreased Haemoglobin A1c (HbA1c) in patients with type 2 diabetes. In an RCT, 170 patients were enrolled from 2018 to 2019 for intervention or control. Inclusion criteria were diagnosed with type 2 diabetes, BMI 30–45 kg/m 2, and aged 18–70 years. Exclusion criteria were lacks internet access, pregnant or planning a pregnancy, or has a serious disease. Primary and secondary outcomes were a reduction in body weight and HbA1c. At six months, 75 (75%) patients in the intervention group and 53 (76%) patients in the control group remained in the trial. The mean body weight loss was 4.2 kg (95% CI, −5.49; −2.98) in the intervention group and 1.5 kg (95% CI, −2.57; −0.48) in the control group (p = 0.005). In the intervention group, 24 out of 62 patients with elevated HbA1c at baseline (39%) had a normalized HbA1c < 6.5% at six months, compared to 8 out of 40 patients with elevated HbA1c at baseline (20%) in the control group (p = 0.047). The eHealth lifestyle coaching programme can lead to significant weight loss and decreased HbA1c among patients with type 2 diabetes, compared to standard care.",

keywords = "Denmark, Diabetes Mellitus, Type 2/therapy, Glycated Hemoglobin A/analysis, Humans, Life Style, Mentoring, Primary Health Care, Telemedicine, Weight Loss, telemedicine, health behaviour change, digital behavioural coaching, lifestyle change, mobile intervention, participant engagement, interactive advice, quality of life, obesity",

author = "Christensen, {Jeanette Reffstrup} and Laursen, {Ditte Hjorth} and Lauridsen, {J{\o}rgen Tranekj{\ae}r} and Laura Hesseldal and Jakobsen, {Pernille Ravn} and Nielsen, {Jesper Bo} and Jens S{\o}ndergaard and Brandt, {Carl Joakim}",

year = "2022",

month = aug,

day = "19",

doi = "10.3390/nu14163424",

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T1 - Reversing Type 2 Diabetes in a Primary Care-Anchored eHealth Lifestyle Coaching Programme in Denmark

T2 - A Randomised Controlled Trial

AU - Christensen, Jeanette Reffstrup

AU - Laursen, Ditte Hjorth

AU - Lauridsen, Jørgen Tranekjær

AU - Hesseldal, Laura

AU - Jakobsen, Pernille Ravn

AU - Nielsen, Jesper Bo

AU - Søndergaard, Jens

AU - Brandt, Carl Joakim

PY - 2022/8/19

Y1 - 2022/8/19

N2 - The goal of this trial was to investigate whether an eHealth lifestyle coaching programme led to significant weight loss and decreased Haemoglobin A1c (HbA1c) in patients with type 2 diabetes. In an RCT, 170 patients were enrolled from 2018 to 2019 for intervention or control. Inclusion criteria were diagnosed with type 2 diabetes, BMI 30–45 kg/m 2, and aged 18–70 years. Exclusion criteria were lacks internet access, pregnant or planning a pregnancy, or has a serious disease. Primary and secondary outcomes were a reduction in body weight and HbA1c. At six months, 75 (75%) patients in the intervention group and 53 (76%) patients in the control group remained in the trial. The mean body weight loss was 4.2 kg (95% CI, −5.49; −2.98) in the intervention group and 1.5 kg (95% CI, −2.57; −0.48) in the control group (p = 0.005). In the intervention group, 24 out of 62 patients with elevated HbA1c at baseline (39%) had a normalized HbA1c < 6.5% at six months, compared to 8 out of 40 patients with elevated HbA1c at baseline (20%) in the control group (p = 0.047). The eHealth lifestyle coaching programme can lead to significant weight loss and decreased HbA1c among patients with type 2 diabetes, compared to standard care.

AB - The goal of this trial was to investigate whether an eHealth lifestyle coaching programme led to significant weight loss and decreased Haemoglobin A1c (HbA1c) in patients with type 2 diabetes. In an RCT, 170 patients were enrolled from 2018 to 2019 for intervention or control. Inclusion criteria were diagnosed with type 2 diabetes, BMI 30–45 kg/m 2, and aged 18–70 years. Exclusion criteria were lacks internet access, pregnant or planning a pregnancy, or has a serious disease. Primary and secondary outcomes were a reduction in body weight and HbA1c. At six months, 75 (75%) patients in the intervention group and 53 (76%) patients in the control group remained in the trial. The mean body weight loss was 4.2 kg (95% CI, −5.49; −2.98) in the intervention group and 1.5 kg (95% CI, −2.57; −0.48) in the control group (p = 0.005). In the intervention group, 24 out of 62 patients with elevated HbA1c at baseline (39%) had a normalized HbA1c < 6.5% at six months, compared to 8 out of 40 patients with elevated HbA1c at baseline (20%) in the control group (p = 0.047). The eHealth lifestyle coaching programme can lead to significant weight loss and decreased HbA1c among patients with type 2 diabetes, compared to standard care.

KW - Denmark

KW - Diabetes Mellitus, Type 2/therapy

KW - Glycated Hemoglobin A/analysis

KW - Humans

KW - Life Style

KW - Mentoring

KW - Primary Health Care

KW - Telemedicine

KW - Weight Loss

KW - telemedicine

KW - health behaviour change

KW - digital behavioural coaching

KW - lifestyle change

KW - mobile intervention

KW - participant engagement

KW - interactive advice

KW - quality of life

KW - obesity

U2 - 10.3390/nu14163424

DO - 10.3390/nu14163424

M3 - Journal article

C2 - 36014930

SN - 2072-6643

VL - 14

JO - Nutrients

JF - Nutrients

IS - 16

M1 - 3424

ER -

Reversing Type 2 Diabetes in a Primary Care-Anchored eHealth Lifestyle Coaching Programme in Denmark: A Randomised Controlled Trial

Abstract

Keywords

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