Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria

Vera A Essuman, Christine T Ntim-Amponsah, Birgitte Schmidt Astrup, George O Adjei, Jorgen A L Kurtzhals, Thomas A Ndanu, Bamenla Goka

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been described. Detection of this retinopathy could be a useful diagnostic tool. This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children. Secondly, to determine any association between retinopathy and the occurrence of convulsions in patients with CM.
Original languageEnglish
JournalMalaria Journal
Volume9
Pages (from-to)232
ISSN1475-2875
DOIs
Publication statusPublished - 1. Jan 2010

Keywords

  • African Continental Ancestry Group
  • Antimalarials
  • Brain Ischemia
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Ghana
  • Humans
  • Infant
  • Malaria
  • Malaria, Cerebral
  • Male
  • Ophthalmoscopy
  • Parasitemia
  • Plasmodium falciparum
  • Prognosis
  • Quinine
  • Retinal Diseases
  • Severity of Illness Index

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