Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase

F E Nielsen; H T Sørensen; J H Christensen; L Ravn; S E Rasmussen

doi:10.1093/oxfordjournals.eurheartj.a059841

Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase

F E Nielsen, H T Sørensen, J H Christensen, L Ravn, S E Rasmussen

Aalborg University Hospital

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

In a historical follow-up study of 152 hospital patients with acute myocardial infarction, the frequency of life-threatening arrhythmias (ventricular fibrillation, sustained ventricular tachycardia, 3rd degree AV-block, 2nd degree AV-block (Mobitz type II), and asystole) and atrial fibrillation in 76 patients treated with streptokinase was compared with their frequency in 76 patients who did not receive a thrombolytic therapy. Among those treated with streptokinase two patients (3%) developed atrial fibrillation, compared with 12 (16%) in the control group (P = 0.009). Life-threatening arrhythmias occurred with equal frequency in the two groups. Further studies should confirm and clarify the mechanism of the reduced frequency of atrial fibrillation in the streptokinase-treated patients.

Original language	English
Journal	European Heart Journal
Volume	12
Issue number	10
Pages (from-to)	1081-3
Number of pages	3
ISSN	0195-668X
DOIs	https://doi.org/10.1093/oxfordjournals.eurheartj.a059841
Publication status	Published - 1991

Keywords

Aged
Arrhythmias, Cardiac
Atrial Fibrillation
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Infarction
Streptokinase
Journal Article

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10.1093/oxfordjournals.eurheartj.a059841

Cite this

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title = "Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase",

abstract = "In a historical follow-up study of 152 hospital patients with acute myocardial infarction, the frequency of life-threatening arrhythmias (ventricular fibrillation, sustained ventricular tachycardia, 3rd degree AV-block, 2nd degree AV-block (Mobitz type II), and asystole) and atrial fibrillation in 76 patients treated with streptokinase was compared with their frequency in 76 patients who did not receive a thrombolytic therapy. Among those treated with streptokinase two patients (3%) developed atrial fibrillation, compared with 12 (16%) in the control group (P = 0.009). Life-threatening arrhythmias occurred with equal frequency in the two groups. Further studies should confirm and clarify the mechanism of the reduced frequency of atrial fibrillation in the streptokinase-treated patients.",

keywords = "Aged, Arrhythmias, Cardiac, Atrial Fibrillation, Female, Follow-Up Studies, Humans, Male, Middle Aged, Myocardial Infarction, Streptokinase, Journal Article",

author = "Nielsen, {F E} and S{\o}rensen, {H T} and Christensen, {J H} and L Ravn and Rasmussen, {S E}",

year = "1991",

doi = "10.1093/oxfordjournals.eurheartj.a059841",

language = "English",

volume = "12",

pages = "1081--3",

journal = "European Heart Journal",

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T1 - Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase

AU - Nielsen, F E

AU - Sørensen, H T

AU - Christensen, J H

AU - Ravn, L

AU - Rasmussen, S E

PY - 1991

Y1 - 1991

N2 - In a historical follow-up study of 152 hospital patients with acute myocardial infarction, the frequency of life-threatening arrhythmias (ventricular fibrillation, sustained ventricular tachycardia, 3rd degree AV-block, 2nd degree AV-block (Mobitz type II), and asystole) and atrial fibrillation in 76 patients treated with streptokinase was compared with their frequency in 76 patients who did not receive a thrombolytic therapy. Among those treated with streptokinase two patients (3%) developed atrial fibrillation, compared with 12 (16%) in the control group (P = 0.009). Life-threatening arrhythmias occurred with equal frequency in the two groups. Further studies should confirm and clarify the mechanism of the reduced frequency of atrial fibrillation in the streptokinase-treated patients.

AB - In a historical follow-up study of 152 hospital patients with acute myocardial infarction, the frequency of life-threatening arrhythmias (ventricular fibrillation, sustained ventricular tachycardia, 3rd degree AV-block, 2nd degree AV-block (Mobitz type II), and asystole) and atrial fibrillation in 76 patients treated with streptokinase was compared with their frequency in 76 patients who did not receive a thrombolytic therapy. Among those treated with streptokinase two patients (3%) developed atrial fibrillation, compared with 12 (16%) in the control group (P = 0.009). Life-threatening arrhythmias occurred with equal frequency in the two groups. Further studies should confirm and clarify the mechanism of the reduced frequency of atrial fibrillation in the streptokinase-treated patients.

KW - Aged

KW - Arrhythmias, Cardiac

KW - Atrial Fibrillation

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Streptokinase

KW - Journal Article

U2 - 10.1093/oxfordjournals.eurheartj.a059841

DO - 10.1093/oxfordjournals.eurheartj.a059841

M3 - Journal article

C2 - 1782933

SN - 0195-668X

VL - 12

SP - 1081

EP - 1083

JO - European Heart Journal

JF - European Heart Journal

IS - 10

ER -

Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase

Abstract

Keywords

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