Quality of life of children with type 1 diabetes

a systematic review

Anke M Nieuwesteeg, Frans Pouwer, Rozemarijn van der Kamp, Hedwig J A van Bakel, Henk-Jan Aanstoot, Esther E Hartman

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

INTRODUCTION: Children with type 1 diabetes mellitus (T1DM) have to deal with a complex and demanding daily treatment regime which can have a negative impact on the quality of life (QoL) of these patients. The objective of the present study is to review studies that have compared generic quality of life of children and adolescents with T1DM with that of healthy peers. In addition, we will examine whether QoL differs between boys and girls, and across different developmental stages.

METHODS: A systematic literature search using PubMed was conducted for the years 2000 through May 2012. 17 studies were eligible for the current review. Effect sizes were computed to estimate the effects of having T1DM on QoL in children and adolescents.

RESULTS: Although individual studies reported small to moderate effect sizes on the distinct QoL-domains, the weighted effect sizes across all studies indicated no differences in QoL-domains between children and adolescents with T1DM and healthy controls. However, disease-specific problems were certainly present. Girls with T1DM reported lower generic and disease-specific QoL than boys with T1DM. Relationships between age and generic or disease-specific QoL remained unclear.

CONCLUSIONS: Although children and adolescents with T1DM have to live with a demanding treatment regime, overall results revealed that their generic QoL is not impaired compared to healthy peers. However, disease-specific QoL problems, including a negative impact of diabetes on daily functioning, and diabetes-related worries were certainly present. Longitudinal research is needed in order to provide tailored care for children of all ages with T1DM.

Original languageEnglish
JournalCurrent Diabetes Reviews
Volume8
Issue number6
Pages (from-to)434-443
ISSN1573-3998
DOIs
Publication statusPublished - 2012
Externally publishedYes

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Keywords

  • Adolescent
  • Adolescent Health Services
  • Adult
  • Age of Onset
  • Child
  • Child Health Services
  • Child, Preschool
  • Diabetes Mellitus, Type 1
  • Female
  • Health Status
  • Humans
  • Infant
  • Male
  • Parents
  • Quality of Life
  • Surveys and Questionnaires
  • Journal Article
  • Review

Cite this

Nieuwesteeg, A. M., Pouwer, F., van der Kamp, R., van Bakel, H. J. A., Aanstoot, H-J., & Hartman, E. E. (2012). Quality of life of children with type 1 diabetes: a systematic review. Current Diabetes Reviews, 8(6), 434-443. https://doi.org/10.2174/157339912803529850
Nieuwesteeg, Anke M ; Pouwer, Frans ; van der Kamp, Rozemarijn ; van Bakel, Hedwig J A ; Aanstoot, Henk-Jan ; Hartman, Esther E. / Quality of life of children with type 1 diabetes : a systematic review. In: Current Diabetes Reviews. 2012 ; Vol. 8, No. 6. pp. 434-443.
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abstract = "INTRODUCTION: Children with type 1 diabetes mellitus (T1DM) have to deal with a complex and demanding daily treatment regime which can have a negative impact on the quality of life (QoL) of these patients. The objective of the present study is to review studies that have compared generic quality of life of children and adolescents with T1DM with that of healthy peers. In addition, we will examine whether QoL differs between boys and girls, and across different developmental stages.METHODS: A systematic literature search using PubMed was conducted for the years 2000 through May 2012. 17 studies were eligible for the current review. Effect sizes were computed to estimate the effects of having T1DM on QoL in children and adolescents.RESULTS: Although individual studies reported small to moderate effect sizes on the distinct QoL-domains, the weighted effect sizes across all studies indicated no differences in QoL-domains between children and adolescents with T1DM and healthy controls. However, disease-specific problems were certainly present. Girls with T1DM reported lower generic and disease-specific QoL than boys with T1DM. Relationships between age and generic or disease-specific QoL remained unclear.CONCLUSIONS: Although children and adolescents with T1DM have to live with a demanding treatment regime, overall results revealed that their generic QoL is not impaired compared to healthy peers. However, disease-specific QoL problems, including a negative impact of diabetes on daily functioning, and diabetes-related worries were certainly present. Longitudinal research is needed in order to provide tailored care for children of all ages with T1DM.",
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Nieuwesteeg, AM, Pouwer, F, van der Kamp, R, van Bakel, HJA, Aanstoot, H-J & Hartman, EE 2012, 'Quality of life of children with type 1 diabetes: a systematic review', Current Diabetes Reviews, vol. 8, no. 6, pp. 434-443. https://doi.org/10.2174/157339912803529850

Quality of life of children with type 1 diabetes : a systematic review. / Nieuwesteeg, Anke M; Pouwer, Frans; van der Kamp, Rozemarijn; van Bakel, Hedwig J A; Aanstoot, Henk-Jan; Hartman, Esther E.

In: Current Diabetes Reviews, Vol. 8, No. 6, 2012, p. 434-443.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Quality of life of children with type 1 diabetes

T2 - a systematic review

AU - Nieuwesteeg, Anke M

AU - Pouwer, Frans

AU - van der Kamp, Rozemarijn

AU - van Bakel, Hedwig J A

AU - Aanstoot, Henk-Jan

AU - Hartman, Esther E

PY - 2012

Y1 - 2012

N2 - INTRODUCTION: Children with type 1 diabetes mellitus (T1DM) have to deal with a complex and demanding daily treatment regime which can have a negative impact on the quality of life (QoL) of these patients. The objective of the present study is to review studies that have compared generic quality of life of children and adolescents with T1DM with that of healthy peers. In addition, we will examine whether QoL differs between boys and girls, and across different developmental stages.METHODS: A systematic literature search using PubMed was conducted for the years 2000 through May 2012. 17 studies were eligible for the current review. Effect sizes were computed to estimate the effects of having T1DM on QoL in children and adolescents.RESULTS: Although individual studies reported small to moderate effect sizes on the distinct QoL-domains, the weighted effect sizes across all studies indicated no differences in QoL-domains between children and adolescents with T1DM and healthy controls. However, disease-specific problems were certainly present. Girls with T1DM reported lower generic and disease-specific QoL than boys with T1DM. Relationships between age and generic or disease-specific QoL remained unclear.CONCLUSIONS: Although children and adolescents with T1DM have to live with a demanding treatment regime, overall results revealed that their generic QoL is not impaired compared to healthy peers. However, disease-specific QoL problems, including a negative impact of diabetes on daily functioning, and diabetes-related worries were certainly present. Longitudinal research is needed in order to provide tailored care for children of all ages with T1DM.

AB - INTRODUCTION: Children with type 1 diabetes mellitus (T1DM) have to deal with a complex and demanding daily treatment regime which can have a negative impact on the quality of life (QoL) of these patients. The objective of the present study is to review studies that have compared generic quality of life of children and adolescents with T1DM with that of healthy peers. In addition, we will examine whether QoL differs between boys and girls, and across different developmental stages.METHODS: A systematic literature search using PubMed was conducted for the years 2000 through May 2012. 17 studies were eligible for the current review. Effect sizes were computed to estimate the effects of having T1DM on QoL in children and adolescents.RESULTS: Although individual studies reported small to moderate effect sizes on the distinct QoL-domains, the weighted effect sizes across all studies indicated no differences in QoL-domains between children and adolescents with T1DM and healthy controls. However, disease-specific problems were certainly present. Girls with T1DM reported lower generic and disease-specific QoL than boys with T1DM. Relationships between age and generic or disease-specific QoL remained unclear.CONCLUSIONS: Although children and adolescents with T1DM have to live with a demanding treatment regime, overall results revealed that their generic QoL is not impaired compared to healthy peers. However, disease-specific QoL problems, including a negative impact of diabetes on daily functioning, and diabetes-related worries were certainly present. Longitudinal research is needed in order to provide tailored care for children of all ages with T1DM.

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KW - Adult

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KW - Child, Preschool

KW - Diabetes Mellitus, Type 1

KW - Female

KW - Health Status

KW - Humans

KW - Infant

KW - Male

KW - Parents

KW - Quality of Life

KW - Surveys and Questionnaires

KW - Journal Article

KW - Review

U2 - 10.2174/157339912803529850

DO - 10.2174/157339912803529850

M3 - Journal article

VL - 8

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EP - 443

JO - Current Diabetes Reviews

JF - Current Diabetes Reviews

SN - 1573-3998

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ER -