[Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]

R. M. Smeenk, V. J. Verwaal, F. A. Zoetmulder

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Abstract

Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after initial treatment, the second patient had died of disease progression but the other two were alive and free of disease. Pseudomyxoma peritonei is a rare disease, characterised by progressive intraperitoneal accumulation of mucinous ascites, produced by a mucinous tumour mass on the peritoneal surfaces. The primary tumour is usually a mucinous adenoma of the appendix. Treatment by cytoreductive surgery and HIPEC can result in a 5-year survival rate of more than 80%, depending on the histopathology and the completeness of the cytoreduction. Recognising pseudomyxoma peritonei in an early stage, when complete cytoreduction is still achievable, may result in a considerable improvement in survival.
Original languageEnglish
JournalNederlands Tijdschrift voor Geneeskunde
Volume151
Issue number7
Pages (from-to)418-423
Number of pages6
ISSN0028-2162
Publication statusPublished - 2007
Externally publishedYes

Bibliographical note

Smeenk, R M Verwaal, V J Zoetmulder, F A N dut Case Reports English Abstract Netherlands 2007/03/09 09:00 Ned Tijdschr Geneeskd. 2007 Feb 17;151(7):418-23.

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