Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after initial treatment, the second patient had died of disease progression but the other two were alive and free of disease. Pseudomyxoma peritonei is a rare disease, characterised by progressive intraperitoneal accumulation of mucinous ascites, produced by a mucinous tumour mass on the peritoneal surfaces. The primary tumour is usually a mucinous adenoma of the appendix. Treatment by cytoreductive surgery and HIPEC can result in a 5-year survival rate of more than 80%, depending on the histopathology and the completeness of the cytoreduction. Recognising pseudomyxoma peritonei in an early stage, when complete cytoreduction is still achievable, may result in a considerable improvement in survival.
|Journal||Nederlands Tijdschrift voor Geneeskunde|
|Number of pages||6|
|Publication status||Published - 2007|
Bibliographical noteSmeenk, R M Verwaal, V J Zoetmulder, F A N dut Case Reports English Abstract Netherlands 2007/03/09 09:00 Ned Tijdschr Geneeskd. 2007 Feb 17;151(7):418-23.
Smeenk, R. M., Verwaal, V. J., & Zoetmulder, F. A. (2007). [Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy]. Nederlands Tijdschrift voor Geneeskunde, 151(7), 418-423.