Pseudohyponatraemia caused by acute pancreatitis-derived hypertriglyceridaemia

Rasmus Søgaard Hansen*, Jesper Revsholm, Mohammad Motawea, Lars Folkestad

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review


We report a case of pseudohyponatraemia due to severe hypertriglyceridaemia-induced acute pancreatitis, stemming from unknown diabetes. A woman in her late 30s was admitted to the local hospital by her general practitioner due to severe hyponatraemia (116 mmol/L) and upper abdominal pain. At admission to the hospital, there was a discrepancy of 19 mmol/L between arterial and venous sodium, along with severe hypertriglyceridaemia and hypercholesterolaemia. Pancreatitis was diagnosed using a CT scan. The patient received plasmapheresis which significantly reduced triglycerides, and venous plasma sodium was normalised indicating pseudohyponatraemia at admission. Finally, a haemoglobin A1c of 83 mmol/mol was found. Diabetes was diagnosed, and insulin was initiated.

Original languageEnglish
JournalBMJ Case Reports
Issue number4
Publication statusPublished - 19. Apr 2021


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