TY - JOUR
T1 - Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark
AU - Madsen, Anne Marie Rosendahl
AU - Thorsteinsson, Kristina
AU - Lebech, Anne-Mette
AU - Storgaard, Merete
AU - Katzenstein, Terese L
AU - Rönsholt, Frederikke F
AU - Johansen, Isik Somuncu
AU - Pedersen, Gitte
AU - Nielsen, Lars Noerregaard
AU - Andersen, Aase Bengaard
AU - Jensen, Jørgen Skov
PY - 2017/9/7
Y1 - 2017/9/7
N2 - OBJECTIVE: Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status. 234 women, recruited from Danish HIV centres as part of a larger observational study on aspects of living with HIV as a woman (the SHADE study), were included.RESULTS: We tested cervical samples for M. genitalium by specific PCR. We found three samples positive (1.3%). The women were between 30 and 50 years old, all were of Asian origin, sexually active, and on antiretroviral treatment with supressed HIV RNA and CD4 count >350 cells/µL. None reported symptoms from the lower abdomen. The prevalence of M. genitalium infection in WLWH in Denmark is low, thus systematic screening for M. genitalium in this group does not seem relevant.
AB - OBJECTIVE: Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status. 234 women, recruited from Danish HIV centres as part of a larger observational study on aspects of living with HIV as a woman (the SHADE study), were included.RESULTS: We tested cervical samples for M. genitalium by specific PCR. We found three samples positive (1.3%). The women were between 30 and 50 years old, all were of Asian origin, sexually active, and on antiretroviral treatment with supressed HIV RNA and CD4 count >350 cells/µL. None reported symptoms from the lower abdomen. The prevalence of M. genitalium infection in WLWH in Denmark is low, thus systematic screening for M. genitalium in this group does not seem relevant.
KW - HIV
KW - Mycoplasma genitalium
KW - Sexually transmitted diseases
KW - Women living with HIV
U2 - 10.1186/s13104-017-2776-5
DO - 10.1186/s13104-017-2776-5
M3 - Journal article
C2 - 28882163
SN - 1756-0500
VL - 10
JO - BMC Research Notes
JF - BMC Research Notes
M1 - 468
ER -