Preparation of organocobalt(iii) complexesviaO2activation

Mads Sondrup Møller, Jacob Kongsted, Christine J. McKenzie*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The coupling of selective C-H activation with O2activation is an important goal for organic synthesis. New experimental and computational results, along with the results from experimental work accumulated over many decades, now unequivocally link O2activation with C-H activation by the classic Co(salen) complexes. A common holistic mechanistic framework can rationalise the formation of ostensibly diverse peroxo, superoxo, organo and alkoxide complexes of CoIII(salen). DFT calculations show that cobalt(iii)superoxo, dicobalt(iii)peroxo and cobalt(iii)hydroperoxo complexes are all viable intermediates as participants in hydrogen atom transfer reactions, whereas a Co(iv)oxo intermediate is unlikely. The reaction conditions will determine the pathway followed and all pathways are initiated through the initial formation of a superoxo complex, CoIII(salen)(O2?)(MeOH) (EPR:g= 2.025,A= 19 G). Organo and alkoxide ligands are derived from solvent media and the trends in reactivity reveal that combination of the pKaand BDE of the C-H of the respective solvent substrates are important. These data explain why landmark, structurally characterized, µ2-?1,?2-peroxide and ?1-superoxide Co(salen)-O2adducts were predominantly isolated from solvents with high C-H pKavalues (DMSO, DMF, DMA).

Original languageEnglish
JournalDalton Transactions
Volume50
Issue number14
Pages (from-to)4819-4829
ISSN1477-9226
DOIs
Publication statusPublished - 14. Apr 2021

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2021.

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