Prenatal characteristics of false negative cases from first-trimester screening of Down syndrome (trisomy 21)

Tanja Schlaikjær Simonsen, Jeppe Steen Sørensen, Charlotte Kvist Ekelund, Finn Stener Jørgensen, Danish Fetal Medicine Research Group, Lene Søndergaard Sperling, Annette Wind Olesen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

What's already known about this topic? In DS cases, maternal age, NT and hCGβ (multiples of median) are high, whereas PAPP-A (multiples of median) is low. What does this study add? This study describes in details the distribution of maternal age, NT, crown rump length and biochemical markers of false negative cases from the first-trimester combined screening for DS.

Original languageEnglish
JournalPrenatal Diagnosis
Volume33
Issue number4
Pages (from-to)400-402
ISSN0197-3851
DOIs
Publication statusPublished - Apr 2013

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