Predicting falls in community-dwelling older adults: A systematic review of prognostic models

Gustav Valentin Gade*, Martin Grønbech Jørgensen, Jesper Ryg, Johannes Riis, Katja Thomsen, Tahir Masud, Stig Andersen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

1012 Downloads (Pure)

Abstract

Objective To systematically review and critically appraise prognostic models for falls in community-dwelling older adults. Eligibility criteria Prospective cohort studies with any follow-up period. Studies had to develop or validate multifactorial prognostic models for falls in community-dwelling older adults (60+ years). Models had to be applicable for screening in a general population setting. Information source MEDLINE, EMBASE, CINAHL, The Cochrane Library, PsycINFO and Web of Science for studies published in English, Danish, Norwegian or Swedish until January 2020. Sources also included trial registries, clinical guidelines, reference lists of included papers, along with contacting clinical experts to locate published studies. Data extraction and risk of bias Two authors performed all review stages independently. Data extraction followed the Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies checklist. Risk of bias assessments on participants, predictors, outcomes and analysis methods followed Prediction study Risk Of Bias Assessment Tool. Results After screening 11 789 studies, 30 were eligible for inclusion (n=86 369 participants). Median age of participants ranged from 67.5 to 83.0 years. Falls incidences varied from 5.9% to 59%. Included studies reported 69 developed and three validated prediction models. Most frequent falls predictors were prior falls, age, sex, measures of gait, balance and strength, along with vision and disability. The area under the curve was available for 40 (55.6%) models, ranging from 0.49 to 0.87. Validated models' The area under the curve ranged from 0.62 to 0.69. All models had a high risk of bias, mostly due to limitations in statistical methods, outcome assessments and restrictive eligibility criteria. Conclusions An abundance of prognostic models on falls risk have been developed, but with a wide range in discriminatory performance. All models exhibited a high risk of bias rendering them unreliable for prediction in clinical practice. Future prognostic prediction models should comply with recent recommendations such as Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis. PROSPERO registration number CRD42019124021.

Original languageEnglish
Article numbere044170
JournalBMJ Open
Volume11
Issue number5
ISSN2044-6055
DOIs
Publication statusPublished - 4. May 2021

Bibliographical note

Publisher Copyright:
© 2021 EDP Sciences. All rights reserved.

Keywords

  • geriatric medicine
  • public health
  • statistics & research methods

Fingerprint

Dive into the research topics of 'Predicting falls in community-dwelling older adults: A systematic review of prognostic models'. Together they form a unique fingerprint.

Cite this