Positive predictive value of serological diagnostic measures in celiac disease

Peter Toftedal, Christian Nielsen, Jonas Trolle Madsen, Kjell Titlestad, Steffen Husby, Søren Thue Lillevang

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Celiac disease (CD) antibodies, immunoglobulin A (IgA) anti-tissue transglutaminase (anti-tTG), IgA endomysium antibody (EMA), IgA and IgG anti-gliadin antibodies (IgA and IgG AGA) are first-line diagnostic tools used in selecting patients for duodenal biopsy. The goal of this study was to evaluate the diagnostic quality of serological testing for CD.
Original languageEnglish
JournalClinical Chemistry and Laboratory Medicine
Volume48
Issue number5
Pages (from-to)685-91
Number of pages7
ISSN1434-6621
DOIs
Publication statusPublished - 1. May 2010

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Celiac Disease
  • Child
  • Child, Preschool
  • Duodenum
  • Female
  • GTP-Binding Proteins
  • Gliadin
  • Humans
  • Immunoglobulin A
  • Immunoglobulin G
  • Infant
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Regression Analysis
  • Serologic Tests
  • Transglutaminases

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