Plasma concentrations and pharmacokinetics of bupivacaine with and without adrenaline following caudal anaesthesia in infants

Tom Giedsing Hansen, N S Morton, P M Cullen, D G Watson

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The aim of this study was to determine whether the use of adrenaline 1/400000 added to 0.25% bupivacaine significantly delays the systemic absorption of the drug from the caudal epidural space in young infants.
Original languageEnglish
JournalActa Anaesthesiologica Scandinavica
Volume45
Issue number1
Pages (from-to)42-7
Number of pages6
ISSN0001-5172
Publication statusPublished - 2001

Keywords

  • Algorithms
  • Anesthesia, Epidural
  • Anesthetics, Local
  • Bupivacaine
  • Epidural Space
  • Epinephrine
  • Half-Life
  • Humans
  • Infant
  • Vasoconstrictor Agents

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