Perioperativ heparin-bridging er sjældent indiceret

Translated title of the contribution: Perioperative heparin bridging is rarely indicated

Jørn Dalsgaard Nielsen, Anna-Marie Bloch Münster, Steen Elkjær Husted

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Meta-analyses of cohort studies and a recent randomized, placebo-controlled study have shown that perioperative bridging of warfarin therapy with therapeutic doses of heparin results in a multi-fold increase in major bleeding but no reduction in the incidence of thromboembolism. It is time to reconsider heparin bridging: When is heparin bridging superfluous? When is prophylactic dosage indicated? And when is it safe to use therapeutic dosing?
Translated title of the contributionPerioperative heparin bridging is rarely indicated
Original languageDanish
Article numberV12150952
JournalUgeskrift for Læger
Volume178
Issue number12
ISSN0041-5782
Publication statusPublished - 2016
Externally publishedYes

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