Periodiske febersyndromer

Translated title of the contribution: Periodic fever syndromes

Jannik Helweg-Larsen, Ann-Brit Eg Hansen, Sussi Bagge Mortensen, Isik Somuncu Johansen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Periodic fever syndromes (PFS) are characterised by recurrent fever and excessive systemic inflammation. These rare and hereditary syndromes include familial Mediterranean fever, tumour necrosis factor receptor-1 associated periodic syndrome, mevalonate kinase deficiency and cryopyrin-associated periodic syndrome. Each PFS has distinct clinical and genetic features. Availability of improved genetic methods has improved the understanding of the syndromes and diagnostic testing. The main complication is systemic amyloidosis. Targeted biological therapy such as interleukin-1 inhibitors is emerging as an effective treatment.

Original languageDanish
Article numberV11170820
JournalUgeskrift for Laeger
Volume180
Issue number15
ISSN0041-5782
Publication statusPublished - 28. May 2018

Fingerprint

Mevalonate Kinase Deficiency
Cryopyrin-Associated Periodic Syndromes
Familial Mediterranean Fever

Cite this

Helweg-Larsen, J., Hansen, A-B. E., Mortensen, S. B., & Johansen, I. S. (2018). Periodiske febersyndromer. Ugeskrift for Laeger, 180(15), [V11170820].
Helweg-Larsen, Jannik ; Hansen, Ann-Brit Eg ; Mortensen, Sussi Bagge ; Johansen, Isik Somuncu. / Periodiske febersyndromer. In: Ugeskrift for Laeger. 2018 ; Vol. 180, No. 15.
@article{657ce768d9824984928022cbf99d0423,
title = "Periodiske febersyndromer",
abstract = "Periodic fever syndromes (PFS) are characterised by recurrent fever and excessive systemic inflammation. These rare and hereditary syndromes include familial Mediterranean fever, tumour necrosis factor receptor-1 associated periodic syndrome, mevalonate kinase deficiency and cryopyrin-associated periodic syndrome. Each PFS has distinct clinical and genetic features. Availability of improved genetic methods has improved the understanding of the syndromes and diagnostic testing. The main complication is systemic amyloidosis. Targeted biological therapy such as interleukin-1 inhibitors is emerging as an effective treatment.",
keywords = "Hereditary Autoinflammatory Diseases/diagnosis, Humans",
author = "Jannik Helweg-Larsen and Hansen, {Ann-Brit Eg} and Mortensen, {Sussi Bagge} and Johansen, {Isik Somuncu}",
year = "2018",
month = "5",
day = "28",
language = "Dansk",
volume = "180",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "15",

}

Helweg-Larsen, J, Hansen, A-BE, Mortensen, SB & Johansen, IS 2018, 'Periodiske febersyndromer', Ugeskrift for Laeger, vol. 180, no. 15, V11170820.

Periodiske febersyndromer. / Helweg-Larsen, Jannik; Hansen, Ann-Brit Eg; Mortensen, Sussi Bagge; Johansen, Isik Somuncu.

In: Ugeskrift for Laeger, Vol. 180, No. 15, V11170820, 28.05.2018.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Periodiske febersyndromer

AU - Helweg-Larsen, Jannik

AU - Hansen, Ann-Brit Eg

AU - Mortensen, Sussi Bagge

AU - Johansen, Isik Somuncu

PY - 2018/5/28

Y1 - 2018/5/28

N2 - Periodic fever syndromes (PFS) are characterised by recurrent fever and excessive systemic inflammation. These rare and hereditary syndromes include familial Mediterranean fever, tumour necrosis factor receptor-1 associated periodic syndrome, mevalonate kinase deficiency and cryopyrin-associated periodic syndrome. Each PFS has distinct clinical and genetic features. Availability of improved genetic methods has improved the understanding of the syndromes and diagnostic testing. The main complication is systemic amyloidosis. Targeted biological therapy such as interleukin-1 inhibitors is emerging as an effective treatment.

AB - Periodic fever syndromes (PFS) are characterised by recurrent fever and excessive systemic inflammation. These rare and hereditary syndromes include familial Mediterranean fever, tumour necrosis factor receptor-1 associated periodic syndrome, mevalonate kinase deficiency and cryopyrin-associated periodic syndrome. Each PFS has distinct clinical and genetic features. Availability of improved genetic methods has improved the understanding of the syndromes and diagnostic testing. The main complication is systemic amyloidosis. Targeted biological therapy such as interleukin-1 inhibitors is emerging as an effective treatment.

KW - Hereditary Autoinflammatory Diseases/diagnosis

KW - Humans

M3 - Tidsskriftartikel

VL - 180

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 15

M1 - V11170820

ER -

Helweg-Larsen J, Hansen A-BE, Mortensen SB, Johansen IS. Periodiske febersyndromer. Ugeskrift for Laeger. 2018 May 28;180(15). V11170820.