Partial oral treatment of endocarditis

Kasper Iversen, Nis Baun Høst, Niels Eske Bruun, Hanne Elming, Bettina Pump, Jens Jørgen Christensen, Sabine Gill, Flemming Rosenvinge, Henrik Wiggers, Kurt Fuursted, Claus Holst-Hansen, Eva Korup, Henrik Carl Schønheyder, Christian Hassager, Dan Høfsten, Jannik Helweg Larsen, Claus Ernst Moser, Nikolaj Ihlemann, Henning Bundgaard

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.
Original languageEnglish
JournalAmerican Heart Journal
Volume165
Issue number2
Pages (from-to)116-22
Number of pages7
ISSN0002-8703
DOIs
Publication statusPublished - 2013

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Iversen, K., Høst, N. B., Bruun, N. E., Elming, H., Pump, B., Christensen, J. J., ... Bundgaard, H. (2013). Partial oral treatment of endocarditis. American Heart Journal, 165(2), 116-22. https://doi.org/10.1016/j.ahj.2012.11.006
Iversen, Kasper ; Høst, Nis Baun ; Bruun, Niels Eske ; Elming, Hanne ; Pump, Bettina ; Christensen, Jens Jørgen ; Gill, Sabine ; Rosenvinge, Flemming ; Wiggers, Henrik ; Fuursted, Kurt ; Holst-Hansen, Claus ; Korup, Eva ; Schønheyder, Henrik Carl ; Hassager, Christian ; Høfsten, Dan ; Larsen, Jannik Helweg ; Moser, Claus Ernst ; Ihlemann, Nikolaj ; Bundgaard, Henning. / Partial oral treatment of endocarditis. In: American Heart Journal. 2013 ; Vol. 165, No. 2. pp. 116-22.
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title = "Partial oral treatment of endocarditis",
abstract = "Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.",
author = "Kasper Iversen and H{\o}st, {Nis Baun} and Bruun, {Niels Eske} and Hanne Elming and Bettina Pump and Christensen, {Jens J{\o}rgen} and Sabine Gill and Flemming Rosenvinge and Henrik Wiggers and Kurt Fuursted and Claus Holst-Hansen and Eva Korup and Sch{\o}nheyder, {Henrik Carl} and Christian Hassager and Dan H{\o}fsten and Larsen, {Jannik Helweg} and Moser, {Claus Ernst} and Nikolaj Ihlemann and Henning Bundgaard",
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year = "2013",
doi = "10.1016/j.ahj.2012.11.006",
language = "English",
volume = "165",
pages = "116--22",
journal = "American Heart Journal",
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Iversen, K, Høst, NB, Bruun, NE, Elming, H, Pump, B, Christensen, JJ, Gill, S, Rosenvinge, F, Wiggers, H, Fuursted, K, Holst-Hansen, C, Korup, E, Schønheyder, HC, Hassager, C, Høfsten, D, Larsen, JH, Moser, CE, Ihlemann, N & Bundgaard, H 2013, 'Partial oral treatment of endocarditis', American Heart Journal, vol. 165, no. 2, pp. 116-22. https://doi.org/10.1016/j.ahj.2012.11.006

Partial oral treatment of endocarditis. / Iversen, Kasper; Høst, Nis Baun; Bruun, Niels Eske; Elming, Hanne; Pump, Bettina; Christensen, Jens Jørgen; Gill, Sabine; Rosenvinge, Flemming; Wiggers, Henrik; Fuursted, Kurt; Holst-Hansen, Claus; Korup, Eva; Schønheyder, Henrik Carl; Hassager, Christian; Høfsten, Dan; Larsen, Jannik Helweg; Moser, Claus Ernst; Ihlemann, Nikolaj; Bundgaard, Henning.

In: American Heart Journal, Vol. 165, No. 2, 2013, p. 116-22.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Partial oral treatment of endocarditis

AU - Iversen, Kasper

AU - Høst, Nis Baun

AU - Bruun, Niels Eske

AU - Elming, Hanne

AU - Pump, Bettina

AU - Christensen, Jens Jørgen

AU - Gill, Sabine

AU - Rosenvinge, Flemming

AU - Wiggers, Henrik

AU - Fuursted, Kurt

AU - Holst-Hansen, Claus

AU - Korup, Eva

AU - Schønheyder, Henrik Carl

AU - Hassager, Christian

AU - Høfsten, Dan

AU - Larsen, Jannik Helweg

AU - Moser, Claus Ernst

AU - Ihlemann, Nikolaj

AU - Bundgaard, Henning

N1 - Copyright © 2013 Mosby, Inc. All rights reserved.

PY - 2013

Y1 - 2013

N2 - Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.

AB - Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.

U2 - 10.1016/j.ahj.2012.11.006

DO - 10.1016/j.ahj.2012.11.006

M3 - Journal article

C2 - 23351813

VL - 165

SP - 116

EP - 122

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 2

ER -

Iversen K, Høst NB, Bruun NE, Elming H, Pump B, Christensen JJ et al. Partial oral treatment of endocarditis. American Heart Journal. 2013;165(2):116-22. https://doi.org/10.1016/j.ahj.2012.11.006