Opposite-sex and same-sex twin studies of physiological, cognitive and behavioral traits

Linda Juel Ahrenfeldt, Kaare Christensen, Nancy L Segal, Yoon-Mi Hur

Research output: Contribution to journalJournal articleResearchpeer-review

33 Downloads (Pure)

Abstract

A scientific interest in opposite-sex (OS) twins comes from animal studies showing hormone transfer between fetuses in utero. A parallel effect in humans may occur, especially for OS females who may be exposed to androgens, in particular testosterone, from the male co-twin. Conversely, OS males may be exposed to lower levels of prenatal testosterone than do same-sex (SS) males. In this special issue, we reviewed published studies investigating potential differences between OS and SS twins in physiological, cognitive and behavioral traits focusing on the Twin Testosterone Transfer (TTT) hypothesis. Sixty articles fulfilled the eligibility criteria including 23 studies published since the review by Tapp et al. (2011). In general, studies of cognition are conflicting, but it is the phenotype for which most support for the TTT hypothesis is found. Less consistent evidence has been found regarding physiological and behavioral traits. We hope that this special issue will stimulate a discussion about how an investigation of the TTT hypothesis should continue in future research.

Original languageEnglish
JournalNeuroscience & Biobehavioral Reviews
Volume108
Pages (from-to)322-340
ISSN0149-7634
DOIs
Publication statusPublished - Jan 2020

Keywords

  • Behavior
  • Cognition
  • Masculinization
  • Opposite-sex
  • Physiology
  • Same-sex
  • Sex differences
  • Testosterone
  • Twins

Fingerprint

Dive into the research topics of 'Opposite-sex and same-sex twin studies of physiological, cognitive and behavioral traits'. Together they form a unique fingerprint.

Cite this