Opioider mod refraktær dyspnø i palliativ fase

Translated title of the contribution: Opioids for refractory dyspnoea in palliation

Birgit Åbom, Elisabeth Bendstrup, Per Sjøgren, Anders Løkke Ottesen, Saher Burhan Shaker, Jon Torgny Wilcke, Bodil Abild Jespersen, Ole Hilberg, Kristoffer Marsaa

Research output: Contribution to journalJournal articleResearchpeer-review


Dyspnoea is cardinal symptom in chronic obstructive lung disease and common in palliative phases of cancer and other chronic medical diseases. Low-dose opioids is frequently used off-label. This review examines the evidence and safety as well as administration forms and pharmacokinetics using low dose opioids for dyspnoea. Conclusively, there seems to be clinical efficacy although further studies are needed. Furthermore, the authors recommend Danish Medical Agency to legislate low-dose morphine to palliative patients with refractory dyspnoea.
Translated title of the contributionOpioids for refractory dyspnoea in palliation
Original languageDanish
Article numberV04200225
JournalUgeskrift for Laeger
Issue number5
Publication statusPublished - 2021


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