Abstract
The N-terminal prohormone B-type natriuretic peptide (NT-proBNP) is involved in the regulation of volume load and secreted when systemic cardiac overload occurs. Fibulin-1 on the other hand is a component of many extracellular matrix proteins including those present in atherosclerotic lesions, expressed in elastin-containing fibres of blood vessels, and also in the heart. Due to an alarming prevalence of hypertensive heart disease in black South Africans, we investigated the associations of NT-proBNP with fibulin-1 and markers of arterial stiffness in Africans and Caucasians.
| Original language | English |
|---|---|
| Journal | Atherosclerosis |
| Volume | 222 |
| Issue number | 1 |
| Pages (from-to) | 216-21 |
| Number of pages | 6 |
| ISSN | 0021-9150 |
| DOIs | |
| Publication status | Published - 2012 |
Keywords
- Adult
- African Continental Ancestry Group
- Aged
- Blood Flow Velocity
- Calcium-Binding Proteins
- Cross-Sectional Studies
- European Continental Ancestry Group
- Female
- Humans
- Male
- Middle Aged
- Natriuretic Peptide, Brain
- Peptide Fragments
- Pulsatile Flow
- South Africa
- Vascular Stiffness
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