NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies

Emil R. Kyvsgaard; Morten Grauslund; Lene Sjø; Linea Cecilie Melchior; Trine Lønbo Grantzau; Lise Mette Rahbek Gjerdrum; Trine Trab; Lærke Sloth Andersen; Anne Ortved Gang; Marie Breinholt; Michael Boe Møller; Jacob Haaber Christensen; Thomas Stauffer Larsen; Michael Roost Clausen; Caroline H. Riley; Carsten U. Niemann; Kirsten Grønbæk; Martin Hutchings; Simon Husby

doi:10.1002/ajh.27601

NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies

Emil R. Kyvsgaard, Morten Grauslund, Lene Sjø, Linea Cecilie Melchior, Trine Lønbo Grantzau, Lise Mette Rahbek Gjerdrum, Trine Trab, Lærke Sloth Andersen, Anne Ortved Gang, Marie Breinholt, Michael Boe Møller, Jacob Haaber Christensen, Thomas Stauffer Larsen, Michael Roost Clausen, Caroline H. Riley, Carsten U. Niemann, Kirsten Grønbæk, Martin Hutchings, Simon Husby^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › Research › peer-review

Original language	English
Journal	American Journal of Hematology
ISSN	0361-8609
DOIs	https://doi.org/10.1002/ajh.27601
Publication status	E-pub ahead of print - 2025

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10.1002/ajh.27601

Cite this

Kyvsgaard, E. R., Grauslund, M., Sjø, L., Melchior, L. C., Grantzau, T. L., Gjerdrum, L. M. R., Trab, T., Andersen, L. S., Gang, A. O., Breinholt, M., Møller, M. B., Haaber Christensen, J., Larsen, T. S., Clausen, M. R., Riley, C. H., Niemann, C. U., Grønbæk, K., Hutchings, M., & Husby, S. (2025). NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies. American Journal of Hematology. Advance online publication. https://doi.org/10.1002/ajh.27601

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title = "NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies",

author = "Kyvsgaard, {Emil R.} and Morten Grauslund and Lene Sj{\o} and Melchior, {Linea Cecilie} and Grantzau, {Trine L{\o}nbo} and Gjerdrum, {Lise Mette Rahbek} and Trine Trab and Andersen, {L{\ae}rke Sloth} and Gang, {Anne Ortved} and Marie Breinholt and M{\o}ller, {Michael Boe} and {Haaber Christensen}, Jacob and Larsen, {Thomas Stauffer} and Clausen, {Michael Roost} and Riley, {Caroline H.} and Niemann, {Carsten U.} and Kirsten Gr{\o}nb{\ae}k and Martin Hutchings and Simon Husby",

year = "2025",

doi = "10.1002/ajh.27601",

language = "English",

journal = "American Journal of Hematology",

issn = "0361-8609",

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Kyvsgaard, ER, Grauslund, M, Sjø, L, Melchior, LC, Grantzau, TL, Gjerdrum, LMR, Trab, T, Andersen, LS, Gang, AO, Breinholt, M, Møller, MB , Haaber Christensen, J , Larsen, TS , Clausen, MR, Riley, CH, Niemann, CU, Grønbæk, K, Hutchings, M & Husby, S 2025, 'NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies', American Journal of Hematology. https://doi.org/10.1002/ajh.27601

TY - JOUR

T1 - NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies

AU - Kyvsgaard, Emil R.

AU - Grauslund, Morten

AU - Sjø, Lene

AU - Melchior, Linea Cecilie

AU - Grantzau, Trine Lønbo

AU - Gjerdrum, Lise Mette Rahbek

AU - Trab, Trine

AU - Andersen, Lærke Sloth

AU - Gang, Anne Ortved

AU - Breinholt, Marie

AU - Møller, Michael Boe

AU - Haaber Christensen, Jacob

AU - Larsen, Thomas Stauffer

AU - Clausen, Michael Roost

AU - Riley, Caroline H.

AU - Niemann, Carsten U.

AU - Grønbæk, Kirsten

AU - Hutchings, Martin

AU - Husby, Simon

PY - 2025

Y1 - 2025

U2 - 10.1002/ajh.27601

DO - 10.1002/ajh.27601

M3 - Comment/debate

C2 - 39865309

AN - SCOPUS:85216075783

SN - 0361-8609

JO - American Journal of Hematology

JF - American Journal of Hematology

ER -