No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Abstract

Inflammatory bowel diseases (IBD) are disorders associated to a pathological immune response. Surfactant protein D (SP-D) is part of the innate host defense and has known anti-inflammatory effects. We hypothesize that SP-D dampens dextran sodium sulfate (DSS)-induced colitis by reducing innate inflammatory signaling and facilitation clearance of apoptotic cells. We induced experimental colitis in C57BL/6N Sftpd-/- (KO) and Sftpd+/+ (WT) mice by administration of 1% or 1.5% DSS for 7 days.
Original languageDanish
Publication date2016
Number of pages1
Publication statusPublished - 2016
Event10th European Mucosal Immunology Group Meeting - DGI-Byen, Copenhagen, Denmark
Duration: 19. Oct 201621. Oct 2016
http://emig2016.org/

Conference

Conference10th European Mucosal Immunology Group Meeting
LocationDGI-Byen
CountryDenmark
CityCopenhagen
Period19/10/201621/10/2016
Internet address

Cite this

@conference{7454e725f9e8498b8a0684c7ddfb2391,
title = "No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice",
abstract = "Inflammatory bowel diseases (IBD) are disorders associated to a pathological immune response. Surfactant protein D (SP-D) is part of the innate host defense and has known anti-inflammatory effects. We hypothesize that SP-D dampens dextran sodium sulfate (DSS)-induced colitis by reducing innate inflammatory signaling and facilitation clearance of apoptotic cells. We induced experimental colitis in C57BL/6N Sftpd-/- (KO) and Sftpd+/+ (WT) mice by administration of 1{\%} or 1.5{\%} DSS for 7 days.",
author = "Nex{\o}e, {Anders Bathum} and Bartosz Pilecki and Steffen Husby and Uffe Holmskov and S{\o}rensen, {Grith Lykke}",
year = "2016",
language = "Dansk",
note = "10th European Mucosal Immunology Group Meeting, emig2016 ; Conference date: 19-10-2016 Through 21-10-2016",
url = "http://emig2016.org/",

}

Nexøe, AB, Pilecki, B, Husby, S, Holmskov, U & Sørensen, GL 2016, 'No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice', 10th European Mucosal Immunology Group Meeting, Copenhagen, Denmark, 19/10/2016 - 21/10/2016.

No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice. / Nexøe, Anders Bathum; Pilecki, Bartosz; Husby, Steffen; Holmskov, Uffe; Sørensen, Grith Lykke.

2016. Abstract from 10th European Mucosal Immunology Group Meeting, Copenhagen, Denmark.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

TY - ABST

T1 - No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice

AU - Nexøe, Anders Bathum

AU - Pilecki, Bartosz

AU - Husby, Steffen

AU - Holmskov, Uffe

AU - Sørensen, Grith Lykke

PY - 2016

Y1 - 2016

N2 - Inflammatory bowel diseases (IBD) are disorders associated to a pathological immune response. Surfactant protein D (SP-D) is part of the innate host defense and has known anti-inflammatory effects. We hypothesize that SP-D dampens dextran sodium sulfate (DSS)-induced colitis by reducing innate inflammatory signaling and facilitation clearance of apoptotic cells. We induced experimental colitis in C57BL/6N Sftpd-/- (KO) and Sftpd+/+ (WT) mice by administration of 1% or 1.5% DSS for 7 days.

AB - Inflammatory bowel diseases (IBD) are disorders associated to a pathological immune response. Surfactant protein D (SP-D) is part of the innate host defense and has known anti-inflammatory effects. We hypothesize that SP-D dampens dextran sodium sulfate (DSS)-induced colitis by reducing innate inflammatory signaling and facilitation clearance of apoptotic cells. We induced experimental colitis in C57BL/6N Sftpd-/- (KO) and Sftpd+/+ (WT) mice by administration of 1% or 1.5% DSS for 7 days.

M3 - Konferenceabstrakt til konference

ER -

Nexøe AB, Pilecki B, Husby S, Holmskov U, Sørensen GL. No Ameliorating Effect of Surfactant Protein D on DSS-Induced Colitis in Mice. 2016. Abstract from 10th European Mucosal Immunology Group Meeting, Copenhagen, Denmark.