Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation

Line Bisgaard Jørgensen; Ole Skov; Knud Bonnet Yderstræde

doi:10.1136/bcr-2013-202139

Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation

Line Bisgaard Jørgensen, Ole Skov, Knud Bonnet Yderstræde

Odense University Hospital

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated. The patient had no family history of cardiovascular disease, and all blood sample analyses for hypercoagulability were negative. We recommend an increased focus on peripheral thromboembolism, when treating patients with severe ketoacidosis.

Translated title of the contribution	Nydiagnosticeret type 1 diabetes kompliceret med ketoacidose og perifer trombose medførende femuramputation.
Original language	English
Journal	BMJ Case Reports
Volume	2014
Issue number	May 19
Number of pages	2
ISSN	1757-790X
DOIs	https://doi.org/10.1136/bcr-2013-202139
Publication status	Published - 19. May 2014

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Cite this

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title = "Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation",

abstract = "Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated. The patient had no family history of cardiovascular disease, and all blood sample analyses for hypercoagulability were negative. We recommend an increased focus on peripheral thromboembolism, when treating patients with severe ketoacidosis.",

keywords = "Diabetes Mellitus, Type 1/complications, Peripheral Vascular Diseases, Thromboembolism, Diabetic Ketoacidosis, Amputation",

author = "{Bisgaard J{\o}rgensen}, Line and Ole Skov and Yderstr{\ae}de, {Knud Bonnet}",

year = "2014",

month = may,

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doi = "10.1136/bcr-2013-202139",

language = "English",

volume = "2014",

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T1 - Newly diagnosed type 1 diabetes complicated by ketoacidosis and peripheral thrombosis leading to transfemoral amputation

AU - Bisgaard Jørgensen, Line

AU - Skov, Ole

AU - Yderstræde, Knud Bonnet

PY - 2014/5/19

Y1 - 2014/5/19

N2 - Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated. The patient had no family history of cardiovascular disease, and all blood sample analyses for hypercoagulability were negative. We recommend an increased focus on peripheral thromboembolism, when treating patients with severe ketoacidosis.

AB - Peripheral vascular thromboembolism is a rarely described complication of diabetic ketoacidosis. We report a 41-year-old otherwise healthy man admitted with ketoacidosis and ischaemia of the left foot. The patient was unsuccessfully treated with thromboendarterectomy, and the extremity was ultimately amputated. The patient had no family history of cardiovascular disease, and all blood sample analyses for hypercoagulability were negative. We recommend an increased focus on peripheral thromboembolism, when treating patients with severe ketoacidosis.

KW - Diabetes Mellitus, Type 1/complications

KW - Peripheral Vascular Diseases

KW - Thromboembolism

KW - Diabetic Ketoacidosis

KW - Amputation

U2 - 10.1136/bcr-2013-202139

DO - 10.1136/bcr-2013-202139

M3 - Journal article

C2 - 24842351

SN - 1757-790X

VL - 2014

JO - BMJ Case Reports

JF - BMJ Case Reports

IS - May 19

ER -