New conformationally restricted DNA mimics

Torben Højland, Bolle Ravindra Babu, Jesper Wengel

Research output: Contribution to journalConference articleResearchpeer-review

Abstract

Two novel bicyclic nucleotide monomers have been developed for use as DNA mimics. Melting temperature studies showed that these modifications decrease binding affinity towards complementary DNA and RNA.

Original languageEnglish
Book seriesNucleic Acids Symposium Series
Volume52
Issue number1
Pages (from-to)271-272
ISSN0261-3166
DOIs
Publication statusPublished - 2008
EventNew conformationally restricted DNA mimics -
Duration: 24. Aug 2010 → …

Conference

ConferenceNew conformationally restricted DNA mimics
Period24/08/2010 → …

Fingerprint

Complementary RNA
Freezing
Complementary DNA
DNA

Cite this

Højland, Torben ; Babu, Bolle Ravindra ; Wengel, Jesper. / New conformationally restricted DNA mimics. In: Nucleic Acids Symposium Series. 2008 ; Vol. 52, No. 1. pp. 271-272.
@inproceedings{ef7dfc50dbf311dd9908000ea68e967b,
title = "New conformationally restricted DNA mimics",
abstract = "Two novel bicyclic nucleotide monomers have been developed for use as DNA mimics. Melting temperature studies showed that these modifications decrease binding affinity towards complementary DNA and RNA.",
author = "Torben H{\o}jland and Babu, {Bolle Ravindra} and Jesper Wengel",
note = "Volumne: 52",
year = "2008",
doi = "10.1093/nass/nrn137",
language = "English",
volume = "52",
pages = "271--272",
journal = "Nucleic Acids Symposium Series",
issn = "0261-3166",
publisher = "Heinemann",
number = "1",

}

New conformationally restricted DNA mimics. / Højland, Torben; Babu, Bolle Ravindra; Wengel, Jesper.

In: Nucleic Acids Symposium Series, Vol. 52, No. 1, 2008, p. 271-272.

Research output: Contribution to journalConference articleResearchpeer-review

TY - GEN

T1 - New conformationally restricted DNA mimics

AU - Højland, Torben

AU - Babu, Bolle Ravindra

AU - Wengel, Jesper

N1 - Volumne: 52

PY - 2008

Y1 - 2008

N2 - Two novel bicyclic nucleotide monomers have been developed for use as DNA mimics. Melting temperature studies showed that these modifications decrease binding affinity towards complementary DNA and RNA.

AB - Two novel bicyclic nucleotide monomers have been developed for use as DNA mimics. Melting temperature studies showed that these modifications decrease binding affinity towards complementary DNA and RNA.

U2 - 10.1093/nass/nrn137

DO - 10.1093/nass/nrn137

M3 - Conference article

VL - 52

SP - 271

EP - 272

JO - Nucleic Acids Symposium Series

JF - Nucleic Acids Symposium Series

SN - 0261-3166

IS - 1

ER -