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Nasal CPAP and surfactant for treatment of respiratory distress syndrome and prevention of bronchopulmonary dysplasia

  • Henrik Verder
  • , Kajsa Bohlin
  • , Jens Kamper
  • , Robert Lindwall
  • , Baldvin Jonsson

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The Scandinavian approach is an effective combined treatment for respiratory distress syndrome (RDS) and prevention of bronchopulmonary dysplasia (BPD). It is composed of many individual parts. Of significant importance is the early treatment with nasal continuous positive airway pressure (nCPAP) and surfactant treatment. The approach may be supplemented with caffeine citrate and non-invasive positive pressure ventilation for apnoea. The low incidence of BPD seen as a consequence of the treatment strategy is mainly due to a reduced need for mechanical ventilation (MV). Conclusion: Early-postnatal treatment with nCPAP and surfactant decreases the severity and mortality of RDS and BPD. This is mainly due to a diminished use of MV in the first days of life.
Original languageEnglish
JournalActa Paediatrica
Volume98
Issue number9
Pages (from-to)1400-8
Number of pages8
ISSN0803-5253
DOIs
Publication statusPublished - 1. Sept 2009

Keywords

  • Apnea
  • Bronchopulmonary Dysplasia
  • Caffeine
  • Central Nervous System Stimulants
  • Citrates
  • Combined Modality Therapy
  • Continuous Positive Airway Pressure
  • Humans
  • Infant, Newborn
  • Positive-Pressure Respiration
  • Pulmonary Surfactants
  • Respiration, Artificial
  • Respiratory Distress Syndrome, Newborn

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