N-acetylcysteine improves arterial vascular reactivity in patients with chronic kidney disease

Antje Wittstock, Magdalena Burkert, Walter Zidek, Martin Tepel, Alexandra Scholze

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Patients with stage 5 chronic kidney disease show increased cardiovascular morbidity and mortality that are partly related to impaired arterial vascular reactivity. We investigated whether intravenous administration of the antioxidant acetylcysteine improves arterial vascular reactivity in these patients.
Original languageEnglish
JournalNephron Clinical Practice
Volume112
Issue number3
Pages (from-to)c184-9
ISSN1660-2137
DOIs
Publication statusPublished - 2009

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Acetylcysteine

Keywords

  • Acetylcysteine
  • Aged
  • Female
  • Humans
  • Kidney Failure, Chronic
  • Male
  • Peripheral Vascular Diseases
  • Placebo Effect

Cite this

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title = "N-acetylcysteine improves arterial vascular reactivity in patients with chronic kidney disease",
abstract = "Patients with stage 5 chronic kidney disease show increased cardiovascular morbidity and mortality that are partly related to impaired arterial vascular reactivity. We investigated whether intravenous administration of the antioxidant acetylcysteine improves arterial vascular reactivity in these patients.",
keywords = "Acetylcysteine, Aged, Female, Humans, Kidney Failure, Chronic, Male, Peripheral Vascular Diseases, Placebo Effect",
author = "Antje Wittstock and Magdalena Burkert and Walter Zidek and Martin Tepel and Alexandra Scholze",
note = "Copyright 2009 S. Karger AG, Basel.",
year = "2009",
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journal = "NEPHRON PHYSIOLOGY",
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N-acetylcysteine improves arterial vascular reactivity in patients with chronic kidney disease. / Wittstock, Antje; Burkert, Magdalena; Zidek, Walter; Tepel, Martin; Scholze, Alexandra.

In: Nephron Clinical Practice, Vol. 112, No. 3, 2009, p. c184-9.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - N-acetylcysteine improves arterial vascular reactivity in patients with chronic kidney disease

AU - Wittstock, Antje

AU - Burkert, Magdalena

AU - Zidek, Walter

AU - Tepel, Martin

AU - Scholze, Alexandra

N1 - Copyright 2009 S. Karger AG, Basel.

PY - 2009

Y1 - 2009

N2 - Patients with stage 5 chronic kidney disease show increased cardiovascular morbidity and mortality that are partly related to impaired arterial vascular reactivity. We investigated whether intravenous administration of the antioxidant acetylcysteine improves arterial vascular reactivity in these patients.

AB - Patients with stage 5 chronic kidney disease show increased cardiovascular morbidity and mortality that are partly related to impaired arterial vascular reactivity. We investigated whether intravenous administration of the antioxidant acetylcysteine improves arterial vascular reactivity in these patients.

KW - Acetylcysteine

KW - Aged

KW - Female

KW - Humans

KW - Kidney Failure, Chronic

KW - Male

KW - Peripheral Vascular Diseases

KW - Placebo Effect

U2 - 10.1159/000218107

DO - 10.1159/000218107

M3 - Journal article

C2 - 19439989

VL - 112

SP - c184-9

JO - NEPHRON PHYSIOLOGY

JF - NEPHRON PHYSIOLOGY

SN - 1660-2137

IS - 3

ER -