Myeloid sarcoma developing in pre-existing pyoderma gangrenosum

Ida Bruun Kristensen, Hanne Møller, Mette Wanscher Kjaerskov, Knud Yderstraede, Michael Boe Møller, Olav J Bergmann

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.
Original languageEnglish
JournalActa Dermato-Venereologica
Volume89
Issue number2
Pages (from-to)175-7
Number of pages2
ISSN0001-5555
DOIs
Publication statusPublished - 1. Jan 2009

Keywords

  • Cell Transformation, Neoplastic
  • Female
  • Humans
  • Leg Ulcer
  • Leukemia, Myeloid, Acute
  • Middle Aged
  • Myelodysplastic Syndromes
  • Pyoderma Gangrenosum
  • Sarcoma, Myeloid
  • Skin Neoplasms

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