Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Lars Haukali Omland; Peer Brehm Christensen; Henrik Bygum Krarup; Peter Jepsen; Nina Weis; Henrik Toft Sørensen; Niels Obel; DANVIR Cohort Study; Anna-Marie Bloch Münster

doi:10.1371/journal.pone.0022476

Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Lars Haukali Omland, Peer Brehm Christensen, Henrik Bygum Krarup, Peter Jepsen, Nina Weis, Henrik Toft Sørensen, Niels Obel, DANVIR Cohort Study, Anna-Marie Bloch Münster (Member of author group)

KI, OUH, Research unit of Infectious Diseases (Odense)

Aalborg University Hospital

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.

Original language	English
Article number	e22476
Journal	PLOS ONE
Volume	6
Issue number	7
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0022476
Publication status	Published - 2011

Keywords

Adult
Alcoholism
Cause of Death
Cohort Studies
Comorbidity
Denmark
Female
Hepacivirus
Hepatitis C
Humans
Incidence
Kaplan-Meier Estimate
Male
Middle Aged
Substance Abuse, Intravenous

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10.1371/journal.pone.0022476

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title = "Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study",

abstract = "The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.",

keywords = "Adult, Alcoholism, Cause of Death, Cohort Studies, Comorbidity, Denmark, Female, Hepacivirus, Hepatitis C, Humans, Incidence, Kaplan-Meier Estimate, Male, Middle Aged, Substance Abuse, Intravenous",

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AU - Omland, Lars Haukali

AU - Christensen, Peer Brehm

AU - Krarup, Henrik Bygum

AU - Jepsen, Peter

AU - Weis, Nina

AU - Sørensen, Henrik Toft

AU - Obel, Niels

AU - DANVIR Cohort Study

A2 - Münster, Anna-Marie Bloch

PY - 2011

Y1 - 2011

N2 - The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.

AB - The increased mortality in HCV-infected individuals partly stems from viral damage to the liver and partly from risk-taking behaviours. We examined mortality in patients who cleared their HCV-infection, comparing it to that of the general population. We also addressed the question whether prognosis differed according to age, substance abuse (alcohol abuse and injection drug use) and comorbidity.

KW - Adult

KW - Alcoholism

KW - Cause of Death

KW - Cohort Studies

KW - Comorbidity

KW - Denmark

KW - Female

KW - Hepacivirus

KW - Hepatitis C

KW - Humans

KW - Incidence

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Substance Abuse, Intravenous

U2 - 10.1371/journal.pone.0022476

DO - 10.1371/journal.pone.0022476

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JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 7

M1 - e22476

ER -

Mortality among patients with cleared hepatitis C virus infection compared to the general population: a Danish nationwide cohort study

Abstract

Keywords

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