Longitudinal Changes in Leukocyte Telomere Length and Mortality in Humans

Laila Bendix, Mikael Thinggaard, Mogens Fenger, Steen Kølvraa, Kirsten Avlund, Allan René Linneberg, Merete Osler

Research output: Contribution to journalJournal articleResearchpeer-review


Leukocyte telomere length (LTL) ostensibly shortens with age and has been moderately associated with mortality. In humans, these findings have come almost solely from cross-sectional studies. Only recently has LTL shortening within individuals been analyzed in longitudinal studies. Such studies are relevant to establish LTL dynamics as biomarkers of mortality as well as to disentangle the causality of telomeres on aging.
Original languageEnglish
JournalThe journals of gerontology. Series A, Biological sciences and medical sciences
Volume69 A
Issue number2
Pages (from-to)231-239
Publication statusPublished - Feb 2014


  • Biomarkers
  • DNA damage and repair
  • Epidemiology
  • Longevity
  • Life Style
  • Age Factors
  • Humans
  • Middle Aged
  • Risk Factors
  • Longevity/physiology
  • Male
  • Alcohol Drinking
  • Socioeconomic Factors
  • Telomere Shortening/physiology
  • Adult
  • Female
  • Aged
  • Leukocytes/pathology
  • Health Status
  • Longitudinal Studies
  • Smoking


Dive into the research topics of 'Longitudinal Changes in Leukocyte Telomere Length and Mortality in Humans'. Together they form a unique fingerprint.

Cite this