Influence of postdischarge nutrition on body composition at 6 years of age among children born very preterm.

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Abstract

Background:
New research has shown that type of nutrition in early life may affect not only growth but also later body composition and risk of developing metabolic syndrome.
Method:
A prospective, randomized, interventional multicentre trial on nutrition of a preterm birth cohort has been established and described previously2. Inclusion criteria were gestational age ≤32+0 weeks. From hospital discharge to 4 month corrected aged, the infants received 3 different types of nutrition: A: human milk (HM) B: HM enriched with fortifier C: preterm formula. At 6 years of age, a dexa scan was performed to evaluate body composition.
Results:
277 infants were included, 79 children are investigated now. (A: 26, B: 22 and C: 31). Fat mass (FM) and muscle mass (MM) was measured. FM was highest in group C (formula), and lowest in group A (HM) (A: 15,4%, B: 18,2%, C: 19,7%). The same pattern was found for FM in grams: 3270(A), 3914(B) and 4515(C). FM for group C was higher than group A (p<0,02), group B higher than A (p<0,05). FM for group C was not significantly higher than B. MM was similar in group A (16633 g) and C (16310 g) and higher as compared to B (15841 g), but not significantly.
Conclusion:
It seems that HM is the preferable nutrition for preterm born children if a lower fat mass and higher muscle mass is regarded optimal. The results are not all significant, which might be due to the small sample size. Investigations of the remaining infants are awaited.
Translated title of the contributionKropssammensætning hos 6 årige børn født meget prætermt set i forhold til den tidlige ernæring.
Original languageEnglish
Publication date30. Jan 2014
Number of pages1
Publication statusPublished - 30. Jan 2014
EventInternational Conference on Nutrition & Growth - Barcelona, Spain
Duration: 30. Jan 20141. Feb 2014
Conference number: 2

Conference

ConferenceInternational Conference on Nutrition & Growth
Number2
CountrySpain
CityBarcelona
Period30/01/201401/02/2014

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