Is early reoperation after a cied procedure associated with mortality after 6 months? Results from a complete, nationwide cohort in Denmark

R. Kirkfeldt, J. B. Johansen, E. A. Nohr, O. D. Joergensen, J. C. Nielsen

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Abstract

Purpose: To provide complete and validated data on mortality after cardiac implantable electronic device (CIED) procedures, including pacemakers (PM), cardiac resynchronization therapy devices with defibrillator (CRT-D) or without (CRT-P), and implantable cardioverter defibrillators (ICD). Furthermore, to assess association between early reoperation - and other possible predictors - and all-cause mortality. Methods: A nationwide cohort study was performed including all patients who underwent a CIED procedure in Denmark from May 1 2010 to April 30 2011. Data on reoperations due to a complication were based on an active review of all patient charts while baseline data came from the Danish Pacemaker and ICD Register. Study outcome was 6 months all-cause mortality. Adjusted hazard ratios (aHR) with 95% confidence intervals (CI) were estimated using Cox proportional hazards regression. Early reoperation was entered as a time dependent covariate. Results: The study population consisted of 5,918 consecutive patients; PM: n=4,189, CRT-P: n=209, ICD: n=1,075, CRT-D: n=445. A total of 327 patients (5.5%) died within the first 6 months. No patients died as a direct result of a procedure related complication. We found no significant association between early reoperation and 6 months mortality (aHR 1.6; 95% CI 0.9-3.0), Figure. Mortality was higher if the patient was underweight (aHR 2.6; 95% CI 1.8-3.8), received a single-lead PM (a HR 2.7; 95% CI 2.1- 3.5), or had medium (aHR 1.7; 95% CI 1.2-2.6) or high (aHR 4.0; 95% CI 2.8-5.8) Charlson comorbidity score. We found no association between annual operator volume and mortality. Conclusions: No association was found between early reoperation due to a complication and 6-months all-cause mortality. (Figure Presented).
Original languageEnglish
Article number113
JournalEuropace
Volume17
Issue numberS3
Pages (from-to)iii9
Number of pages1
ISSN1099-5129
Publication statusPublished - 2015
EventEHRA EUROPACE 2015 - Milano , Italy
Duration: 21. Jun 201524. Jun 2015

Conference

ConferenceEHRA EUROPACE 2015
CountryItaly
CityMilano
Period21/06/201524/06/2015

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