Abstract
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among premenopausal women, who often develop insulin resistance. We tested the hypothesis that insulin resistance in skeletal muscle of patients with polycystic ovary syndrome (PCOS) is an intrinsic defect, by investigating the metabolic characteristics and gene expression of in vitro differentiated myotubes established from well characterized PCOS subjects.
Original language | English |
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Journal | PLOS ONE |
Volume | 5 |
Issue number | 12 |
Pages (from-to) | e14469 |
ISSN | 1932-6203 |
DOIs | |
Publication status | Published - 1. Jan 2010 |