Influences of patient informed cognitive complaints on activities of daily living in patients with bipolar disorder. An exploratory cross-sectional study

Conny Träger, Lone Decker, Eva Elisabet Ejlersen Wæhrens, Ulla Knorr, Kamilla Miskowiak, Maj Vinberg

Research output: Contribution to journalJournal articleResearchpeer-review


Many patients with bipolar disorder (BD) experience debilitating cognitive deficits, with risk of impaired
occupational and psychosocial functioning. However, knowledge of how these deficits impact the patients’
ability to perform Activities of Daily Living (ADL), tasks related to self-care and domestic life is limited. We
explored the relation between impaired cognitive function and the ability to perform ADL in patients with BD. A
total of 42 outpatients (mean age 36 years (range 19.0–58.0 years), 69% women) with BD in remission and with
subjective cognitive complaints (≥ 13 on the Cognitive Complaints in Bipolar Disorder Rating Assessment
questionnaire (COBRA)) were included. Objective neurocognitive function was evaluated with a short
comprehensive cognitive test battery and ADL ability was evaluated with the performance-based Assessment
of Motor and Process Skills (AMPS) in the homes of the patients. Our findings indicate that low processing
speed correlated with decreased ADL ability, and processing speed as measured by the cognitive test battery
thus seems to be significantly related to patients’ ability to live independently in the community. Overall, adding
a performance based test to assess ADL ability in patients with BD home-surroundings seems to provide new
insights regarding the effect of cognitive impairment in patients with BD.
Original languageEnglish
JournalPsychiatry Research
Pages (from-to)268-274
Publication statusPublished - Mar 2017


  • Activities of Daily Living/psychology
  • Adult
  • Bipolar Disorder/diagnosis
  • Cognition Disorders/diagnosis
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Self Care
  • Surveys and Questionnaires
  • Young Adult

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