TY - JOUR
T1 - Increase in the heritability of asthma from 1994 to 2003 among adolescent twins
AU - Thomsen, Simon Francis
AU - van der Sluis, Sophie
AU - Kyvik, Kirsten Ohm
AU - Skytthe, Axel
AU - Skadhauge, Lars Rauff
AU - Backer, Vibeke
N1 - Copyright © 2011 Elsevier Ltd. All rights reserved.
PY - 2011
Y1 - 2011
N2 - BACKGROUND: Over the past decades the prevalence of asthma has increased in most parts of the world, and widespread changes in lifestyle and environment have been postulated as the primary cause for this. We examined whether the extent to which genetic and environmental factors influence susceptibility to asthma has changed between 1994 and 2003. METHODS: Two different cohorts of twins (n = 3393 and n = 2813 pairs), both 12-20 years of age, from the Danish Twin Registry, participated in questionnaire studies nine years apart. Prevalence of asthma and resemblance between twins for asthma was compared between the two cohorts. RESULTS: The prevalence of asthma increased from 7.1% in 1994 to 10.8% in 2003, p
AB - BACKGROUND: Over the past decades the prevalence of asthma has increased in most parts of the world, and widespread changes in lifestyle and environment have been postulated as the primary cause for this. We examined whether the extent to which genetic and environmental factors influence susceptibility to asthma has changed between 1994 and 2003. METHODS: Two different cohorts of twins (n = 3393 and n = 2813 pairs), both 12-20 years of age, from the Danish Twin Registry, participated in questionnaire studies nine years apart. Prevalence of asthma and resemblance between twins for asthma was compared between the two cohorts. RESULTS: The prevalence of asthma increased from 7.1% in 1994 to 10.8% in 2003, p
U2 - 10.1016/j.rmed.2011.03.007
DO - 10.1016/j.rmed.2011.03.007
M3 - Journal article
C2 - 21450446
SN - 0954-6111
VL - 105
SP - 1147
EP - 1152
JO - Respiratory Medicine
JF - Respiratory Medicine
IS - 8
ER -