Increase in the heritability of asthma from 1994 to 2003 among adolescent twins

Simon Francis Thomsen, Sophie van der Sluis, Kirsten Ohm Kyvik, Axel Skytthe, Lars Rauff Skadhauge, Vibeke Backer

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

BACKGROUND: Over the past decades the prevalence of asthma has increased in most parts of the world, and widespread changes in lifestyle and environment have been postulated as the primary cause for this. We examined whether the extent to which genetic and environmental factors influence susceptibility to asthma has changed between 1994 and 2003. METHODS: Two different cohorts of twins (n = 3393 and n = 2813 pairs), both 12-20 years of age, from the Danish Twin Registry, participated in questionnaire studies nine years apart. Prevalence of asthma and resemblance between twins for asthma was compared between the two cohorts. RESULTS: The prevalence of asthma increased from 7.1% in 1994 to 10.8% in 2003, p 
Original languageEnglish
JournalRespiratory Medicine
Volume105
Issue number8
Pages (from-to)1147-52
Number of pages5
ISSN0954-6111
DOIs
Publication statusPublished - 2011

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