Improving activities of daily living ability in women with fibromyalgia: An exploratory, quasi-randomized, phase-two study, IMPROvE trial

Cecilie von Bülow, Kirstine Amris, Elisabeth Bandak, Bente Danneskiold-Samsøe, Eva Elisabet Ejlersen Wæhrens

Research output: Contribution to journalJournal articleResearchpeer-review

243 Downloads (Pure)

Abstract

Objective: To explore and compare the outcomes of adaptation and physical activity programmes regarding activities of daily living (ADL) ability following interdisciplinary rehabilitation in women with fibromyalgia. Methods: Participants (n = 85) were quasi-randomized to 16-week adaptation (ADAPT) or physical activity (ACTIVE) programmes following 2-week interdisciplinary rehabilitation. Primary outcomes were ADL motor and ADL process ability, measured with the Assessment of Motor and Process Skills (AMPS) at 4-week follow-up. Data were analysed per protocol. Results: Participants (ADAPT, n = 21; ACTIVE, n = 27) did not differ from withdrawers (n = 37). Improvements in ADL ability in the ADAPT (ADL motor mean change = 0.43 logits (95% confidence interval (95% CI) = 0.31-0.56); ADL process mean change = 0.34 logits (95% CI = 0.17-0.52)) and ACTIVE (ADL motor mean change = 0.33 logits (95% CI = 0.22- 0.43); ADL process mean change = 0.25 logits (95% CI = 0.12-0.38)) groups were statistically significant, with no differences between groups. Responder analyses revealed that 63% of all participants obtained clinically relevant improvements in ADL motor ability and 48% in ADL process ability. Conclusion: Although limited by a large drop-out, this exploratory study showed that both adaptation and physical activity programmes following interdisciplinary rehabilitation improved ADL ability in the majority of participants. ADL ability outcomes were independent of group allocation (ADAPT vs ACTIVE), suggesting efficacy of both programmes.

Original languageEnglish
JournalJournal of Rehabilitation Medicine
Volume49
Issue number3
Pages (from-to)241-250
ISSN1650-1977
DOIs
Publication statusPublished - Mar 2017

Keywords

  • Activities of Daily Living
  • Adult
  • Exercise
  • Female
  • Fibromyalgia/rehabilitation
  • Humans
  • Middle Aged
  • Non-Randomized Controlled Trials as Topic
  • Patient Care Team
  • Patient Dropouts/statistics & numerical data
  • Treatment Outcome

Fingerprint

Dive into the research topics of 'Improving activities of daily living ability in women with fibromyalgia: An exploratory, quasi-randomized, phase-two study, IMPROvE trial'. Together they form a unique fingerprint.

Cite this